7O2L
Yeast 20S proteasome in complex with the covalently bound inhibitor b-lactone (2R,3S)-3-isopropyl-4-oxo-2-oxetane-carboxylate (IOC)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, O | HLJ1_G0039880.mRNA.1.CDS.1 | polymer | 250 | 27191.8 | 2 | UniProt (A0A6L1BIF8) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P23639) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Proteasome subunit alpha type-2 |
| 2 | B, P | BJ4_G0021480.mRNA.1.CDS.1 | polymer | 258 | 28748.2 | 2 | UniProt (A0A6A5PXC6) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P23638) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Proteasome subunit alpha type-3 |
| 3 | C, Q | HLJ1_G0048980.mRNA.1.CDS.1 | polymer | 254 | 28478.1 | 2 | UniProt (A0A6A5Q273) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P40303) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Proteasome subunit alpha type-4 |
| 4 | D, R | 20S proteasome | polymer | 260 | 28649.1 | 2 | UniProt (P32379) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
| 5 | E, S | BJ4_G0043800.mRNA.1.CDS.1 | polymer | 234 | 25634.0 | 2 | UniProt (A0A6A5PTH4) Pfam (PF00227) Pfam (PF10584) UniProt (by SIFTS) (P40302) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Proteasome subunit alpha type-6 |
| 6 | F, T | Probable proteasome subunit alpha type-7 | polymer | 288 | 31575.1 | 2 | UniProt (A0A6A5Q4M4) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P21242) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
| 7 | G, U | BJ4_G0020160.mRNA.1.CDS.1 | polymer | 252 | 28033.8 | 2 | UniProt (A0A6A5PYC9) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P21243) In PDB | Saccharomyces cerevisiae (Baker's yeast) | HLJ1_G0019920.mRNA.1.CDS.1,Proteasome subunit alpha type-1 |
| 8 | H, V | Proteasome endopeptidase complex | polymer | 232 | 25114.5 | 2 | UniProt (A0A6A5Q449) Pfam (PF00227) Pfam (PF12465) UniProt (by SIFTS) (P25043) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
| 9 | I, W | Proteasome endopeptidase complex | polymer | 205 | 22627.8 | 2 | UniProt (A0A6L0YA22) Pfam (PF00227) UniProt (by SIFTS) (P25451) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
| 10 | J, X | Proteasome subunit beta | polymer | 198 | 22545.7 | 2 | UniProt (A0A6A5Q0W2) Pfam (PF00227) UniProt (by SIFTS) (P22141) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
| 11 | K, Y | Proteasome subunit beta type-5 | polymer | 212 | 23325.2 | 2 | UniProt (A0A6V8RU78) Pfam (PF00227) UniProt (by SIFTS) (P30656) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
| 12 | L, Z | Proteasome endopeptidase complex | polymer | 222 | 24883.9 | 2 | UniProt (A0A6A5Q0P3) Pfam (PF00227) UniProt (by SIFTS) (P23724) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
| 13 | M, a | Proteasome subunit beta type-7 | polymer | 246 | 27200.9 | 2 | UniProt (P30657) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4 |
| 14 | N, b | Proteasome endopeptidase complex | polymer | 196 | 21517.2 | 2 | UniProt (A0A6L0ZSP2) Pfam (PF00227) UniProt (by SIFTS) (P38624) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
| 15 | G, I, K, N, V... | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 16 | G, U | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 17 | H, K, N, V, Y... | (2 {R},3 {S})-3-methanoyl-4-methyl-2-hydroxy-pentanoic acid | non-polymer | 160.2 | 6 | Chemie (V08) | |||
| 18 | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 28 |
| Total formula weight | 731050.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1226.4 | |
| All* | Total formula weight | 732277.1 |
