7O2L
Yeast 20S proteasome in complex with the covalently bound inhibitor b-lactone (2R,3S)-3-isopropyl-4-oxo-2-oxetane-carboxylate (IOC)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, O (A, O) | HLJ1_G0039880.mRNA.1.CDS.1 | polymer | 250 | 27191.8 | 2 | UniProt (A0A6L1BIF8) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P23639) | Saccharomyces cerevisiae (Baker's yeast) | Proteasome subunit alpha type-2 |
| 2 | B, P (B, P) | BJ4_G0021480.mRNA.1.CDS.1 | polymer | 258 | 28748.2 | 2 | UniProt (A0A6A5PXC6) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P23638) | Saccharomyces cerevisiae (Baker's yeast) | Proteasome subunit alpha type-3 |
| 3 | C, Q (C, Q) | HLJ1_G0048980.mRNA.1.CDS.1 | polymer | 254 | 28478.1 | 2 | UniProt (A0A6A5Q273) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P40303) | Saccharomyces cerevisiae (Baker's yeast) | Proteasome subunit alpha type-4 |
| 4 | D, R (D, R) | 20S proteasome | polymer | 260 | 28649.1 | 2 | UniProt (P32379) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | |
| 5 | E, S (E, S) | BJ4_G0043800.mRNA.1.CDS.1 | polymer | 234 | 25634.0 | 2 | UniProt (A0A6A5PTH4) Pfam (PF00227) Pfam (PF10584) UniProt (by SIFTS) (P40302) | Saccharomyces cerevisiae (Baker's yeast) | Proteasome subunit alpha type-6 |
| 6 | F, T (F, T) | Probable proteasome subunit alpha type-7 | polymer | 288 | 31575.1 | 2 | UniProt (A0A6A5Q4M4) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P21242) | Saccharomyces cerevisiae (Baker's yeast) | |
| 7 | G, U (G, U) | BJ4_G0020160.mRNA.1.CDS.1 | polymer | 252 | 28033.8 | 2 | UniProt (A0A6A5PYC9) Pfam (PF10584) Pfam (PF00227) UniProt (by SIFTS) (P21243) | Saccharomyces cerevisiae (Baker's yeast) | HLJ1_G0019920.mRNA.1.CDS.1,Proteasome subunit alpha type-1 |
| 8 | H, V (H, V) | Proteasome endopeptidase complex | polymer | 232 | 25114.5 | 2 | UniProt (A0A6A5Q449) Pfam (PF00227) Pfam (PF12465) UniProt (by SIFTS) (P25043) | Saccharomyces cerevisiae (Baker's yeast) | |
| 9 | I, W (I, W) | Proteasome endopeptidase complex | polymer | 205 | 22627.8 | 2 | UniProt (A0A6L0YA22) Pfam (PF00227) UniProt (by SIFTS) (P25451) | Saccharomyces cerevisiae (Baker's yeast) | |
| 10 | J, X (J, X) | Proteasome subunit beta | polymer | 198 | 22545.7 | 2 | UniProt (A0A6A5Q0W2) Pfam (PF00227) UniProt (by SIFTS) (P22141) | Saccharomyces cerevisiae (Baker's yeast) | |
| 11 | K, Y (K, Y) | Proteasome subunit beta type-5 | polymer | 212 | 23325.2 | 2 | UniProt (A0A6V8RU78) Pfam (PF00227) UniProt (by SIFTS) (P30656) | Saccharomyces cerevisiae (Baker's yeast) | |
| 12 | L, Z (L, Z) | Proteasome endopeptidase complex | polymer | 222 | 24883.9 | 2 | UniProt (A0A6A5Q0P3) Pfam (PF00227) UniProt (by SIFTS) (P23724) | Saccharomyces cerevisiae (Baker's yeast) | |
| 13 | AA, M (M, a) | Proteasome subunit beta type-7 | polymer | 246 | 27200.9 | 2 | UniProt (P30657) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4 |
| 14 | BA, N (N, b) | Proteasome endopeptidase complex | polymer | 196 | 21517.2 | 2 | UniProt (A0A6L0ZSP2) Pfam (PF00227) UniProt (by SIFTS) (P38624) | Saccharomyces cerevisiae (Baker's yeast) | |
| 15 | CA, FA, HA, JA, MA... (G, I, K, N, V...) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 16 | DA, KA (G, U) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 17 | EA, GA, IA, LA, OA... (H, K, N, V, Y...) | (2 {R},3 {S})-3-methanoyl-4-methyl-2-hydroxy-pentanoic acid | non-polymer | 160.2 | 6 | Chemie (V08) | |||
| 18 | AB, BB, CB, DB, EB... (I, J, K, L, M...) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 28 |
| Total formula weight | 731050.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1226.4 | |
| All* | Total formula weight | 732277.1 |
