7O0G
Structure of the foamy viral protease-reverse transcriptase in complex with RNA/DNA hybrid.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Pr125Pol | polymer | 752 | 85465.3 | 1 | UniProt (D5JWV1) Pfam (PF03539) Pfam (PF00078) Pfam (PF17919) Pfam (PF00075) In PDB | White-tufted-ear marmoset simian foamy virus | Pro-Pol polyprotein,Protease/Reverse transcriptase,Protease/Reverse transcriptase/ribonuclease H,Ribonuclease H,p42In,p65Pro-RT,p87Pro-RT-RNaseH |
| 2 | E | RNA (5'-R(*UP*UP*CP*UP*UP*GP*UP*CP*CP*AP*GP*GP*AP*GP*AP*GP*G)-3') | polymer | 18 | 5805.5 | 1 | synthetic construct | ||
| 3 | F | DNA (5'-D(*CP*CP*TP*CP*TP*CP*CP*TP*GP*GP*AP*CP*AP*AP*G)-3') | polymer | 15 | 4529.9 | 1 | synthetic construct | ||
| 4 | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 1 - 752 (UniProt: D5JWV1)
| PDB | External Database | Details |
|---|---|---|
| Leu 586 | Unk 586 | variant |
| Asn 598 | Asp 598 | engineered mutation |
| Asn 668 | Asp 668 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 95800.7 | |
| All* | Total formula weight | 95800.7 |
