7NVM
Human TRiC complex in closed state with nanobody Nb18, actin and PhLP2A bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, a | T-complex protein 1 subunit alpha | polymer | 556 | 60418.5 | 2 | UniProt (P17987) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-alpha,CCT-alpha |
| 2 | B, b | T-complex protein 1 subunit beta | polymer | 535 | 57567.1 | 2 | UniProt (P78371) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-beta,CCT-beta |
| 3 | D, d | T-complex protein 1 subunit delta | polymer | 539 | 57996.1 | 2 | UniProt (P50991) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-delta,CCT-delta,Stimulator of TAR RNA-binding |
| 4 | E, e | T-complex protein 1 subunit epsilon | polymer | 541 | 59750.0 | 2 | UniProt (P48643) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-epsilon,CCT-epsilon |
| 5 | G, g | T-complex protein 1 subunit gamma | polymer | 545 | 60613.9 | 2 | UniProt (P49368) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-gamma,CCT-gamma,hTRiC5 |
| 6 | H, h | T-complex protein 1 subunit eta | polymer | 543 | 59443.5 | 2 | UniProt (Q99832) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-eta,CCT-eta,HIV-1 Nef-interacting protein |
| 7 | N, n | Nanobody Nb18 | polymer | 129 | 14412.8 | 2 | Lama glama (llama) | ||
| 8 | Q, q | T-complex protein 1 subunit theta | polymer | 548 | 59691.4 | 2 | UniProt (P50990) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-theta,CCT-theta,Chaperonin containing T-complex polypeptide 1 subunit 8,Renal carcinoma antigen NY-REN-15 |
| 9 | Z, z | T-complex protein 1 subunit zeta | polymer | 531 | 58106.1 | 2 | UniProt (P40227) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-zeta,Acute morphine dependence-related protein 2,CCT-zeta-1,HTR3,Tcp20 |
| 10 | K | Actin, cytoplasmic 2 | polymer | 375 | 41838.8 | 1 | UniProt (P63261) Pfam (PF00022) In PDB | Homo sapiens (Human) | Gamma-actin |
| 11 | P | Phosducin-like protein 3 | polymer | 239 | 27650.4 | 1 | UniProt (Q9H2J4) Pfam (PF02114) In PDB | Homo sapiens (Human) | HTPHLP,PhPL3,Viral IAP-associated factor 1,VIAF-1 |
| 12 | D, e, E, g, G... | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 16 | Chemie (ADP) | |||
| 13 | D, e, E, g, G... | MAGNESIUM ION | non-polymer | 24.3 | 16 | Chemie (MG) | |||
| 14 | d, D, e, E, g... | ALUMINUM FLUORIDE | non-polymer | 84.0 | 16 | Chemie (AF3) | |||
| 15 | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 1045488.0 | |
| Non-Polymers* | Number of molecules | 48 |
| Total formula weight | 8567.7 | |
| All* | Total formula weight | 1054055.7 |
