Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7NVM

Human TRiC complex in closed state with nanobody Nb18, actin and PhLP2A bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000242	cellular_component	pericentriolar material
A	0000792	cellular_component	heterochromatin
A	0001669	cellular_component	acrosomal vesicle
A	0002199	cellular_component	zona pellucida receptor complex
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0005813	cellular_component	centrosome
A	0005815	cellular_component	microtubule organizing center
A	0005829	cellular_component	cytosol
A	0005832	cellular_component	chaperonin-containing T-complex
A	0005856	cellular_component	cytoskeleton
A	0005874	cellular_component	microtubule
A	0006457	biological_process	protein folding
A	0007021	biological_process	tubulin complex assembly
A	0007339	biological_process	binding of sperm to zona pellucida
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0032212	biological_process	positive regulation of telomere maintenance via telomerase
A	0044183	molecular_function	protein folding chaperone
A	0044297	cellular_component	cell body
A	0050821	biological_process	protein stabilization
A	0051082	molecular_function	unfolded protein binding
A	0070062	cellular_component	extracellular exosome
A	0090666	biological_process	scaRNA localization to Cajal body
A	0140535	cellular_component	intracellular protein-containing complex
A	0140662	molecular_function	ATP-dependent protein folding chaperone
A	1904851	biological_process	positive regulation of establishment of protein localization to telomere
A	1904871	biological_process	positive regulation of protein localization to Cajal body
A	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
B	0000166	molecular_function	nucleotide binding
B	0002199	cellular_component	zona pellucida receptor complex
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005832	cellular_component	chaperonin-containing T-complex
B	0005874	cellular_component	microtubule
B	0006457	biological_process	protein folding
B	0007339	biological_process	binding of sperm to zona pellucida
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0031625	molecular_function	ubiquitin protein ligase binding
B	0032212	biological_process	positive regulation of telomere maintenance via telomerase
B	0035578	cellular_component	azurophil granule lumen
B	0044183	molecular_function	protein folding chaperone
B	0044297	cellular_component	cell body
B	0050821	biological_process	protein stabilization
B	0051082	molecular_function	unfolded protein binding
B	0051131	biological_process	chaperone-mediated protein complex assembly
B	0070062	cellular_component	extracellular exosome
B	0090666	biological_process	scaRNA localization to Cajal body
B	0140662	molecular_function	ATP-dependent protein folding chaperone
B	1904871	biological_process	positive regulation of protein localization to Cajal body
B	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
D	0000166	molecular_function	nucleotide binding
D	0002199	cellular_component	zona pellucida receptor complex
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005813	cellular_component	centrosome
D	0005829	cellular_component	cytosol
D	0005832	cellular_component	chaperonin-containing T-complex
D	0005856	cellular_component	cytoskeleton
D	0005874	cellular_component	microtubule
D	0006457	biological_process	protein folding
D	0007339	biological_process	binding of sperm to zona pellucida
D	0016787	molecular_function	hydrolase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0032212	biological_process	positive regulation of telomere maintenance via telomerase
D	0042470	cellular_component	melanosome
D	0042995	cellular_component	cell projection
D	0044183	molecular_function	protein folding chaperone
D	0044297	cellular_component	cell body
D	0050821	biological_process	protein stabilization
D	0051082	molecular_function	unfolded protein binding
D	0070062	cellular_component	extracellular exosome
D	0090666	biological_process	scaRNA localization to Cajal body
D	0140662	molecular_function	ATP-dependent protein folding chaperone
D	1904871	biological_process	positive regulation of protein localization to Cajal body
D	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
E	0000166	molecular_function	nucleotide binding
E	0003730	molecular_function	mRNA 3'-UTR binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005813	cellular_component	centrosome
E	0005829	cellular_component	cytosol
E	0005832	cellular_component	chaperonin-containing T-complex
E	0005856	cellular_component	cytoskeleton
E	0005874	cellular_component	microtubule
E	0006457	biological_process	protein folding
E	0007339	biological_process	binding of sperm to zona pellucida
E	0009615	biological_process	response to virus
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0031681	molecular_function	G-protein beta-subunit binding
E	0032212	biological_process	positive regulation of telomere maintenance via telomerase
E	0044183	molecular_function	protein folding chaperone
E	0044297	cellular_component	cell body
E	0048027	molecular_function	mRNA 5'-UTR binding
E	0048487	molecular_function	beta-tubulin binding
E	0050821	biological_process	protein stabilization
E	0051082	molecular_function	unfolded protein binding
E	0070062	cellular_component	extracellular exosome
E	0140662	molecular_function	ATP-dependent protein folding chaperone
E	1904871	biological_process	positive regulation of protein localization to Cajal body
E	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
G	0000166	molecular_function	nucleotide binding
G	0002199	cellular_component	zona pellucida receptor complex
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005832	cellular_component	chaperonin-containing T-complex
G	0005856	cellular_component	cytoskeleton
G	0005874	cellular_component	microtubule
G	0006457	biological_process	protein folding
G	0007339	biological_process	binding of sperm to zona pellucida
G	0016787	molecular_function	hydrolase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0032212	biological_process	positive regulation of telomere maintenance via telomerase
G	0044183	molecular_function	protein folding chaperone
G	0044297	cellular_component	cell body
G	0050821	biological_process	protein stabilization
G	0051082	molecular_function	unfolded protein binding
G	0070062	cellular_component	extracellular exosome
G	0140662	molecular_function	ATP-dependent protein folding chaperone
G	1904871	biological_process	positive regulation of protein localization to Cajal body
G	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
H	0000166	molecular_function	nucleotide binding
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005832	cellular_component	chaperonin-containing T-complex
H	0005874	cellular_component	microtubule
H	0006457	biological_process	protein folding
H	0007339	biological_process	binding of sperm to zona pellucida
H	0016787	molecular_function	hydrolase activity
H	0016887	molecular_function	ATP hydrolysis activity
H	0032212	biological_process	positive regulation of telomere maintenance via telomerase
H	0042802	molecular_function	identical protein binding
H	0044183	molecular_function	protein folding chaperone
H	0044297	cellular_component	cell body
H	0050821	biological_process	protein stabilization
H	0051082	molecular_function	unfolded protein binding
H	0070062	cellular_component	extracellular exosome
H	0140662	molecular_function	ATP-dependent protein folding chaperone
H	1904871	biological_process	positive regulation of protein localization to Cajal body
H	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
K	0000166	molecular_function	nucleotide binding
K	0001525	biological_process	angiogenesis
K	0001738	biological_process	morphogenesis of a polarized epithelium
K	0005200	molecular_function	structural constituent of cytoskeleton
K	0005515	molecular_function	protein binding
K	0005522	molecular_function	profilin binding
K	0005524	molecular_function	ATP binding
K	0005615	cellular_component	extracellular space
K	0005634	cellular_component	nucleus
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005856	cellular_component	cytoskeleton
K	0005884	cellular_component	actin filament
K	0005886	cellular_component	plasma membrane
K	0005911	cellular_component	cell-cell junction
K	0005925	cellular_component	focal adhesion
K	0007409	biological_process	axonogenesis
K	0010628	biological_process	positive regulation of gene expression
K	0015629	cellular_component	actin cytoskeleton
K	0016020	cellular_component	membrane
K	0016787	molecular_function	hydrolase activity
K	0019901	molecular_function	protein kinase binding
K	0030016	cellular_component	myofibril
K	0030335	biological_process	positive regulation of cell migration
K	0030424	cellular_component	axon
K	0031625	molecular_function	ubiquitin protein ligase binding
K	0031941	cellular_component	filamentous actin
K	0035267	cellular_component	NuA4 histone acetyltransferase complex
K	0035633	biological_process	maintenance of blood-brain barrier
K	0042802	molecular_function	identical protein binding
K	0043296	cellular_component	apical junction complex
K	0044305	cellular_component	calyx of Held
K	0045177	cellular_component	apical part of cell
K	0045202	cellular_component	synapse
K	0045214	biological_process	sarcomere organization
K	0045335	cellular_component	phagocytic vesicle
K	0048870	biological_process	cell motility
K	0051492	biological_process	regulation of stress fiber assembly
K	0051893	biological_process	regulation of focal adhesion assembly
K	0070062	cellular_component	extracellular exosome
K	0070527	biological_process	platelet aggregation
K	0071346	biological_process	cellular response to type II interferon
K	0072562	cellular_component	blood microparticle
K	0090303	biological_process	positive regulation of wound healing
K	0097433	cellular_component	dense body
K	0098685	cellular_component	Schaffer collateral - CA1 synapse
K	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
K	0098974	biological_process	postsynaptic actin cytoskeleton organization
K	0120192	biological_process	tight junction assembly
K	0120220	cellular_component	basal body patch
K	0150111	biological_process	regulation of transepithelial transport
K	1900242	biological_process	regulation of synaptic vesicle endocytosis
K	1902396	biological_process	protein localization to bicellular tight junction
P	0001525	biological_process	angiogenesis
P	0001938	biological_process	positive regulation of endothelial cell proliferation
P	0005515	molecular_function	protein binding
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0005783	cellular_component	endoplasmic reticulum
P	0005829	cellular_component	cytosol
P	0006457	biological_process	protein folding
P	0006915	biological_process	apoptotic process
P	0010628	biological_process	positive regulation of gene expression
P	0030036	biological_process	actin cytoskeleton organization
P	0032991	cellular_component	protein-containing complex
P	0043184	molecular_function	vascular endothelial growth factor receptor 2 binding
P	0044183	molecular_function	protein folding chaperone
P	0045766	biological_process	positive regulation of angiogenesis
P	0048471	cellular_component	perinuclear region of cytoplasm
P	0050730	biological_process	regulation of peptidyl-tyrosine phosphorylation
P	0050821	biological_process	protein stabilization
P	0097356	cellular_component	perinucleolar compartment
P	1903333	biological_process	negative regulation of protein folding
P	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
Q	0000166	molecular_function	nucleotide binding
Q	0002199	cellular_component	zona pellucida receptor complex
Q	0005515	molecular_function	protein binding
Q	0005524	molecular_function	ATP binding
Q	0005576	cellular_component	extracellular region
Q	0005737	cellular_component	cytoplasm
Q	0005813	cellular_component	centrosome
Q	0005829	cellular_component	cytosol
Q	0005832	cellular_component	chaperonin-containing T-complex
Q	0005856	cellular_component	cytoskeleton
Q	0005874	cellular_component	microtubule
Q	0005929	cellular_component	cilium
Q	0006457	biological_process	protein folding
Q	0007339	biological_process	binding of sperm to zona pellucida
Q	0016787	molecular_function	hydrolase activity
Q	0016887	molecular_function	ATP hydrolysis activity
Q	0032212	biological_process	positive regulation of telomere maintenance via telomerase
Q	0034774	cellular_component	secretory granule lumen
Q	0035578	cellular_component	azurophil granule lumen
Q	0042995	cellular_component	cell projection
Q	0044183	molecular_function	protein folding chaperone
Q	0044297	cellular_component	cell body
Q	0045296	molecular_function	cadherin binding
Q	0050821	biological_process	protein stabilization
Q	0051082	molecular_function	unfolded protein binding
Q	0070062	cellular_component	extracellular exosome
Q	0140662	molecular_function	ATP-dependent protein folding chaperone
Q	1904813	cellular_component	ficolin-1-rich granule lumen
Q	1904871	biological_process	positive regulation of protein localization to Cajal body
Q	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
Z	0000166	molecular_function	nucleotide binding
Z	0003723	molecular_function	RNA binding
Z	0005515	molecular_function	protein binding
Z	0005524	molecular_function	ATP binding
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0005832	cellular_component	chaperonin-containing T-complex
Z	0005874	cellular_component	microtubule
Z	0006457	biological_process	protein folding
Z	0016787	molecular_function	hydrolase activity
Z	0016887	molecular_function	ATP hydrolysis activity
Z	0032212	biological_process	positive regulation of telomere maintenance via telomerase
Z	0044183	molecular_function	protein folding chaperone
Z	0050821	biological_process	protein stabilization
Z	0051082	molecular_function	unfolded protein binding
Z	0070062	cellular_component	extracellular exosome
Z	0071987	molecular_function	WD40-repeat domain binding
Z	0140662	molecular_function	ATP-dependent protein folding chaperone
Z	1904851	biological_process	positive regulation of establishment of protein localization to telomere
Z	1904871	biological_process	positive regulation of protein localization to Cajal body
Z	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
a	0000166	molecular_function	nucleotide binding
a	0000242	cellular_component	pericentriolar material
a	0000792	cellular_component	heterochromatin
a	0001669	cellular_component	acrosomal vesicle
a	0002199	cellular_component	zona pellucida receptor complex
a	0003723	molecular_function	RNA binding
a	0005515	molecular_function	protein binding
a	0005524	molecular_function	ATP binding
a	0005737	cellular_component	cytoplasm
a	0005794	cellular_component	Golgi apparatus
a	0005813	cellular_component	centrosome
a	0005815	cellular_component	microtubule organizing center
a	0005829	cellular_component	cytosol
a	0005832	cellular_component	chaperonin-containing T-complex
a	0005856	cellular_component	cytoskeleton
a	0005874	cellular_component	microtubule
a	0006457	biological_process	protein folding
a	0007021	biological_process	tubulin complex assembly
a	0007339	biological_process	binding of sperm to zona pellucida
a	0016787	molecular_function	hydrolase activity
a	0016887	molecular_function	ATP hydrolysis activity
a	0031625	molecular_function	ubiquitin protein ligase binding
a	0032212	biological_process	positive regulation of telomere maintenance via telomerase
a	0044183	molecular_function	protein folding chaperone
a	0044297	cellular_component	cell body
a	0050821	biological_process	protein stabilization
a	0051082	molecular_function	unfolded protein binding
a	0070062	cellular_component	extracellular exosome
a	0090666	biological_process	scaRNA localization to Cajal body
a	0140535	cellular_component	intracellular protein-containing complex
a	0140662	molecular_function	ATP-dependent protein folding chaperone
a	1904851	biological_process	positive regulation of establishment of protein localization to telomere
a	1904871	biological_process	positive regulation of protein localization to Cajal body
a	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
b	0000166	molecular_function	nucleotide binding
b	0002199	cellular_component	zona pellucida receptor complex
b	0005515	molecular_function	protein binding
b	0005524	molecular_function	ATP binding
b	0005576	cellular_component	extracellular region
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005832	cellular_component	chaperonin-containing T-complex
b	0005874	cellular_component	microtubule
b	0006457	biological_process	protein folding
b	0007339	biological_process	binding of sperm to zona pellucida
b	0016787	molecular_function	hydrolase activity
b	0016887	molecular_function	ATP hydrolysis activity
b	0031625	molecular_function	ubiquitin protein ligase binding
b	0032212	biological_process	positive regulation of telomere maintenance via telomerase
b	0035578	cellular_component	azurophil granule lumen
b	0044183	molecular_function	protein folding chaperone
b	0044297	cellular_component	cell body
b	0050821	biological_process	protein stabilization
b	0051082	molecular_function	unfolded protein binding
b	0051131	biological_process	chaperone-mediated protein complex assembly
b	0070062	cellular_component	extracellular exosome
b	0090666	biological_process	scaRNA localization to Cajal body
b	0140662	molecular_function	ATP-dependent protein folding chaperone
b	1904871	biological_process	positive regulation of protein localization to Cajal body
b	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
d	0000166	molecular_function	nucleotide binding
d	0002199	cellular_component	zona pellucida receptor complex
d	0003723	molecular_function	RNA binding
d	0005515	molecular_function	protein binding
d	0005524	molecular_function	ATP binding
d	0005654	cellular_component	nucleoplasm
d	0005737	cellular_component	cytoplasm
d	0005813	cellular_component	centrosome
d	0005829	cellular_component	cytosol
d	0005832	cellular_component	chaperonin-containing T-complex
d	0005856	cellular_component	cytoskeleton
d	0005874	cellular_component	microtubule
d	0006457	biological_process	protein folding
d	0007339	biological_process	binding of sperm to zona pellucida
d	0016787	molecular_function	hydrolase activity
d	0016887	molecular_function	ATP hydrolysis activity
d	0032212	biological_process	positive regulation of telomere maintenance via telomerase
d	0042470	cellular_component	melanosome
d	0042995	cellular_component	cell projection
d	0044183	molecular_function	protein folding chaperone
d	0044297	cellular_component	cell body
d	0050821	biological_process	protein stabilization
d	0051082	molecular_function	unfolded protein binding
d	0070062	cellular_component	extracellular exosome
d	0090666	biological_process	scaRNA localization to Cajal body
d	0140662	molecular_function	ATP-dependent protein folding chaperone
d	1904871	biological_process	positive regulation of protein localization to Cajal body
d	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
e	0000166	molecular_function	nucleotide binding
e	0003730	molecular_function	mRNA 3'-UTR binding
e	0005515	molecular_function	protein binding
e	0005524	molecular_function	ATP binding
e	0005737	cellular_component	cytoplasm
e	0005813	cellular_component	centrosome
e	0005829	cellular_component	cytosol
e	0005832	cellular_component	chaperonin-containing T-complex
e	0005856	cellular_component	cytoskeleton
e	0005874	cellular_component	microtubule
e	0006457	biological_process	protein folding
e	0007339	biological_process	binding of sperm to zona pellucida
e	0009615	biological_process	response to virus
e	0016787	molecular_function	hydrolase activity
e	0016887	molecular_function	ATP hydrolysis activity
e	0031681	molecular_function	G-protein beta-subunit binding
e	0032212	biological_process	positive regulation of telomere maintenance via telomerase
e	0044183	molecular_function	protein folding chaperone
e	0044297	cellular_component	cell body
e	0048027	molecular_function	mRNA 5'-UTR binding
e	0048487	molecular_function	beta-tubulin binding
e	0050821	biological_process	protein stabilization
e	0051082	molecular_function	unfolded protein binding
e	0070062	cellular_component	extracellular exosome
e	0140662	molecular_function	ATP-dependent protein folding chaperone
e	1904871	biological_process	positive regulation of protein localization to Cajal body
e	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
g	0000166	molecular_function	nucleotide binding
g	0002199	cellular_component	zona pellucida receptor complex
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0005524	molecular_function	ATP binding
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0005832	cellular_component	chaperonin-containing T-complex
g	0005856	cellular_component	cytoskeleton
g	0005874	cellular_component	microtubule
g	0006457	biological_process	protein folding
g	0007339	biological_process	binding of sperm to zona pellucida
g	0016787	molecular_function	hydrolase activity
g	0016887	molecular_function	ATP hydrolysis activity
g	0032212	biological_process	positive regulation of telomere maintenance via telomerase
g	0044183	molecular_function	protein folding chaperone
g	0044297	cellular_component	cell body
g	0050821	biological_process	protein stabilization
g	0051082	molecular_function	unfolded protein binding
g	0070062	cellular_component	extracellular exosome
g	0140662	molecular_function	ATP-dependent protein folding chaperone
g	1904871	biological_process	positive regulation of protein localization to Cajal body
g	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
h	0000166	molecular_function	nucleotide binding
h	0005515	molecular_function	protein binding
h	0005524	molecular_function	ATP binding
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0005832	cellular_component	chaperonin-containing T-complex
h	0005874	cellular_component	microtubule
h	0006457	biological_process	protein folding
h	0007339	biological_process	binding of sperm to zona pellucida
h	0016787	molecular_function	hydrolase activity
h	0016887	molecular_function	ATP hydrolysis activity
h	0032212	biological_process	positive regulation of telomere maintenance via telomerase
h	0042802	molecular_function	identical protein binding
h	0044183	molecular_function	protein folding chaperone
h	0044297	cellular_component	cell body
h	0050821	biological_process	protein stabilization
h	0051082	molecular_function	unfolded protein binding
h	0070062	cellular_component	extracellular exosome
h	0140662	molecular_function	ATP-dependent protein folding chaperone
h	1904871	biological_process	positive regulation of protein localization to Cajal body
h	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
q	0000166	molecular_function	nucleotide binding
q	0002199	cellular_component	zona pellucida receptor complex
q	0005515	molecular_function	protein binding
q	0005524	molecular_function	ATP binding
q	0005576	cellular_component	extracellular region
q	0005737	cellular_component	cytoplasm
q	0005813	cellular_component	centrosome
q	0005829	cellular_component	cytosol
q	0005832	cellular_component	chaperonin-containing T-complex
q	0005856	cellular_component	cytoskeleton
q	0005874	cellular_component	microtubule
q	0005929	cellular_component	cilium
q	0006457	biological_process	protein folding
q	0007339	biological_process	binding of sperm to zona pellucida
q	0016787	molecular_function	hydrolase activity
q	0016887	molecular_function	ATP hydrolysis activity
q	0032212	biological_process	positive regulation of telomere maintenance via telomerase
q	0034774	cellular_component	secretory granule lumen
q	0035578	cellular_component	azurophil granule lumen
q	0042995	cellular_component	cell projection
q	0044183	molecular_function	protein folding chaperone
q	0044297	cellular_component	cell body
q	0045296	molecular_function	cadherin binding
q	0050821	biological_process	protein stabilization
q	0051082	molecular_function	unfolded protein binding
q	0070062	cellular_component	extracellular exosome
q	0140662	molecular_function	ATP-dependent protein folding chaperone
q	1904813	cellular_component	ficolin-1-rich granule lumen
q	1904871	biological_process	positive regulation of protein localization to Cajal body
q	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
z	0000166	molecular_function	nucleotide binding
z	0003723	molecular_function	RNA binding
z	0005515	molecular_function	protein binding
z	0005524	molecular_function	ATP binding
z	0005737	cellular_component	cytoplasm
z	0005829	cellular_component	cytosol
z	0005832	cellular_component	chaperonin-containing T-complex
z	0005874	cellular_component	microtubule
z	0006457	biological_process	protein folding
z	0016787	molecular_function	hydrolase activity
z	0016887	molecular_function	ATP hydrolysis activity
z	0032212	biological_process	positive regulation of telomere maintenance via telomerase
z	0044183	molecular_function	protein folding chaperone
z	0050821	biological_process	protein stabilization
z	0051082	molecular_function	unfolded protein binding
z	0070062	cellular_component	extracellular exosome
z	0071987	molecular_function	WD40-repeat domain binding
z	0140662	molecular_function	ATP-dependent protein folding chaperone
z	1904851	biological_process	positive regulation of establishment of protein localization to telomere
z	1904871	biological_process	positive regulation of protein localization to Cajal body
z	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	26
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGDGTTSVTVlAaellreaesl........IAKK

Chain	Residue	Details
B	VAL95-LYS120

site_id	PS00141
Number of Residues	12
Details	ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. AIADTGANVVVT

Chain	Residue	Details
Q	ALA282-THR293

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
K	TYR53-GLY63

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WISKqEYDE

Chain	Residue	Details
K	TRP356-GLU364

site_id	PS00750
Number of Residues	13
Details	TCP1_1 Chaperonins TCP-1 signature 1. RTnLGPkGtmKML

Chain	Residue	Details
Z	ARG35-LEU47
B	LYS40-LEU52
A	LYS33-LEU45
H	ARG37-ILE49
G	ARG38-LEU50
E	ARG49-MET61
D	ARG49-ILE61
Q	ARG44-VAL56

site_id	PS00751
Number of Residues	17
Details	TCP1_2 Chaperonins TCP-1 signature 2. LTKDGNVLLheMqIqHP

Chain	Residue	Details
Z	LEU56-PRO72
B	VAL63-PRO79
A	ILE54-PRO70
H	ILE58-PRO74
G	MET59-PRO75
E	VAL70-GLN86
D	ILE70-PRO86
Q	VAL65-PRO81

site_id	PS00995
Number of Residues	9
Details	TCP1_3 Chaperonins TCP-1 signature 3. QDdiTGDGT

Chain	Residue	Details
Z	GLN84-THR92
B	GLN91-THR99
A	GLN82-THR90
H	GLN86-THR94
G	GLN87-THR95
E	GLN98-THR106
D	GLN98-THR106
Q	GLN93-THR101

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
K	LEU104-ARG116

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N-acetylmethionine => ECO:0000269\|PubMed:26059764

Chain	Residue	Details
P	MET1
z	ALA2

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:23186163

Chain	Residue	Details
P	SER43
Z	LYS287
z	LYS5
z	LYS287

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692

Chain	Residue	Details
P	SER234
P	SER236
Z	LYS377
Z	LYS388
z	LYS199
z	LYS365
z	LYS377
z	LYS388

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Tele-methylhistidine => ECO:0000269\|PubMed:30626964, ECO:0000269\|Ref.8

Chain	Residue	Details
K	HIS73
q	SER537
e	LYS210
e	LYS214
e	LYS265
e	LYS275
e	LYS279
e	LYS392
z	SER205
Q	SER269
Q	SER317
Q	SER537
q	SER162
q	SER213
q	SER269
q	SER317

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-methyllysine => ECO:0000269\|PubMed:23673617

Chain	Residue	Details
K	LYS84
Q	LYS400
z	LYS251
q	LYS318
q	LYS400
q	LYS466

site_id	SWS_FT_FI6
Number of Residues	1
Details	CROSSLNK: (Microbial infection) Isoglutamyl lysine isopeptide (Lys-Glu) (interchain with E-270); by Vibrio toxins RtxA and VgrG1 => ECO:0000305\|PubMed:19015515

Chain	Residue	Details
K	LYS50
q	TYR505

site_id	SWS_FT_FI7
Number of Residues	2
Details	CROSSLNK: (Microbial infection) Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-50); by Vibrio toxins RtxA and VgrG1 => ECO:0000305\|PubMed:19015515

Chain	Residue	Details
Q	LYS224
K	GLU270
Q	LYS260
q	LYS224
q	LYS254
q	LYS260

site_id	SWS_FT_FI8
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:25755297, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
G	THR430
Q	LYS539
g	THR430
q	LYS539

site_id	SWS_FT_FI9
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0007744\|PubMed:25114211

Chain	Residue	Details
Q	LYS459
q	LYS459
G	LYS249
g	LYS15
g	LYS248
g	LYS249

site_id	SWS_FT_FI10
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:25218447, ECO:0007744\|PubMed:25755297, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
Q	LYS534
q	LYS534
g	LYS381

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)