7NUH

Influenza A/California/07/2009(H1N1) endonuclease with I38T mutation in complex with orientin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Polymerase acidic protein,Polymerase acidic protein	polymer	180	21196.1	1	UniProt (C3W5X6)	Influenza A virus (A/California/07/2009(H1N1))	RNA-directed RNA polymerase subunit P2,RNA-directed RNA polymerase subunit P2
2	B, C (A)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
3	D (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	E, F (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
5	G, H, I, J (A)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
6	K (A)	Orientin	non-polymer		448.4	1	Chemie (USE)
7	L (A)	water	water		18.0	192	Chemie (HOH)

Sequence modifications

A: 1 - null (UniProt: C3W5X6)

PDB	External Database	Details
Ser -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Thr 38	Ile 38	engineered mutation
-	Phe 51	deletion
-	His 52	deletion
-	Phe 53	deletion
-	Ile 54	deletion
-	Asp 55	deletion
-	Glu 56	deletion
-	Arg 57	deletion
-	Gly 58	deletion
-	Glu 59	deletion
-	Ser 60	deletion
-	Ile 61	deletion
-	Ile 62	deletion
-	Val 63	deletion
-	Glu 64	deletion
-	Ser 65	deletion
-	Gly 66	deletion
-	Asp 67	deletion
-	Pro 68	deletion
-	Asn 69	deletion
-	Ala 70	deletion
-	Leu 71	deletion
-	Leu 72	deletion
Gly 51	-	linker
Gly 52	-	linker
Ser 53	-	linker

A: 73 - 196 (UniProt: C3W5X6)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	21196.1
Non-Polymers*	Number of molecules	10
	Total formula weight	1043.1
All*	Total formula weight	22239.2

*Water molecules are not included.