7NTU
X-ray structure of the complex between human alpha thrombin and two duplex/quadruplex aptamers: NU172 and HD22_27mer
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Prothrombin | polymer | 36 | 4096.5 | 2 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (Human) | Coagulation factor II |
2 | B, D | Prothrombin | polymer | 259 | 29780.2 | 2 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (Human) | Coagulation factor II |
3 | E, G | NU172 | polymer | 26 | 8172.2 | 2 | synthetic construct | ||
4 | F, I | HD22_27mer | polymer | 27 | 8485.4 | 2 | synthetic construct | ||
5 | B, D | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 2 | BIRD (PRD_000020) Chemie (0G6) | |||
6 | B, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
7 | E, F, G, I | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
8 | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 101068.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1442.3 | |
All* | Total formula weight | 102511.2 |