7NQ4
Human tRNA guanine transglycosylase (TGT), RNA-bound covalent intermediate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Queuine tRNA-ribosyltransferase catalytic subunit 1 | polymer | 405 | 44251.8 | 1 | UniProt (Q9BXR0) Pfam (PF01702) | Homo sapiens (Human) | Guanine insertion enzyme,tRNA-guanine transglycosylase |
| 2 | B (B) | Queuine tRNA-ribosyltransferase accessory subunit 2 | polymer | 415 | 46775.7 | 1 | UniProt (Q9H974) Pfam (PF01702) | Homo sapiens (Human) | Queuine tRNA-ribosyltransferase domain-containing protein 1 |
| 3 | C (C) | RNA | polymer | 20 | 6421.9 | 1 | synthetic construct | ||
| 4 | D, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | E (A) | 9-DEAZAGUANINE | non-polymer | 150.1 | 1 | Chemie (9DG) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 1 - 403 (UniProt: Q9BXR0)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 97449.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 281.0 | |
| All* | Total formula weight | 97730.3 |
