7NOY
Crystal structure of the heterocyclic toxin methyltransferase from Mycobacterium tuberculosis in complex with substrate 1-hydroxyquinolin-4(1H)-one
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Uncharacterized protein Rv0560c | polymer | 245 | 26420.5 | 1 | UniProt (P9WKL5) Pfam (PF13649) In PDB | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
2 | A | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
3 | A | 1-oxidanylquinolin-4-one | non-polymer | 161.2 | 1 | Chemie (UK5) | |||
4 | A | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
5 | water | water | 18.0 | 282 | Chemie (HOH) |
Sequence modifications
A: 4 - 227 (UniProt: P9WKL5)
PDB | External Database | Details |
---|---|---|
Met -17 | - | initiating methionine |
Gly -16 | - | expression tag |
Ser -15 | - | expression tag |
Ser -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
Glu -5 | - | expression tag |
Asn -4 | - | expression tag |
Leu -3 | - | expression tag |
Tyr -2 | - | expression tag |
Phe -1 | - | expression tag |
Gln 0 | - | expression tag |
Ser 1 | - | expression tag |
Ala 2 | - | expression tag |
Gly 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 26420.5 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 614.5 | |
All* | Total formula weight | 27035.0 |