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7NMZ

Structure of 14-3-3 eta in complex with Nedd4-2(335-455) containing two 14-3-3 binding motifs Ser342 and Ser448

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(AA, BA)
14-3-3 protein etapolymer23627186.82UniProt (Q04917)
Pfam (PF00244)
Homo sapiens (Human)Protein AS1
2C
(C)
E3 ubiquitin-protein ligase NEDD4-likepolymer12513442.61UniProt (Q96PU5)
Pfam (PF00397)
Homo sapiens (Human)HECT-type E3 ubiquitin transferase NED4L,NEDD4.2,Nedd4-2
3D, E, F
(AA, BA, C)
waterwater18.0189Chemie (HOH)
Sequence modifications
AA, BA: 3 - 236 (UniProt: Q04917)
PDBExternal DatabaseDetails
Gly 1-expression tag
His 2-expression tag
C: 335 - 455 (UniProt: Q96PU5)
PDBExternal DatabaseDetails
Gly 331-expression tag
Ala 332-expression tag
Met 333-expression tag
Gly 334-expression tag
Ala 367Thr 367engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight67816.1
All*Total formula weight67816.1
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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