7NMU
Crystal structure of human platelet glycoprotein VI in complex with an inhibitory nanobody.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAA, BBB) | Platelet glycoprotein VI | polymer | 194 | 21270.0 | 2 | UniProt (Q9HCN6) Pfam (PF13895) Pfam (PF13927) | Homo sapiens (Human) | GPVI,Glycoprotein 6 |
| 2 | C, D (DDD, CCC) | Nanobody 2 | polymer | 130 | 14271.7 | 2 | Lama glama | ||
| 3 | E (CCC) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | F, G, H, I (AAA, BBB, DDD, CCC) | water | water | 18.0 | 269 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 6 - 188 (UniProt: Q9HCN6)
| PDB | External Database | Details |
|---|---|---|
| Asp 1 | - | expression tag |
| Lys 2 | - | expression tag |
| Leu 3 | - | expression tag |
| Ala 4 | - | expression tag |
| Ser 5 | - | expression tag |
| Gln 76 | Asn 92 | engineered mutation |
| Asp 189 | - | expression tag |
| Pro 190 | - | expression tag |
| Ile 191 | - | expression tag |
| Glu 192 | - | expression tag |
| Gly 193 | - | expression tag |
| Arg 194 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 71083.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 71123.6 |
