7NMU

Crystal structure of human platelet glycoprotein VI in complex with an inhibitory nanobody.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	AAA, BBB	Platelet glycoprotein VI	polymer	194	21270.0	2	UniProt (Q9HCN6) Pfam (PF13895) Pfam (PF13927) In PDB	Homo sapiens (Human)	GPVI,Glycoprotein 6
2	DDD, CCC	Nanobody 2	polymer	130	14271.7	2		Lama glama
3	CCC	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
4		water	water		18.0	269	Chemie (HOH)

Sequence modifications

AAA, BBB: 6 - 188 (UniProt: Q9HCN6)

PDB	External Database	Details
Asp 1	-	expression tag
Lys 2	-	expression tag
Leu 3	-	expression tag
Ala 4	-	expression tag
Ser 5	-	expression tag
Gln 76	Asn 92	engineered mutation
Asp 189	-	expression tag
Pro 190	-	expression tag
Ile 191	-	expression tag
Glu 192	-	expression tag
Gly 193	-	expression tag
Arg 194	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	71083.5
Non-Polymers*	Number of molecules	1
	Total formula weight	40.1
All*	Total formula weight	71123.6

*Water molecules are not included.