7NLD

Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (C, A, B, D, E...)	Programmed cell death 1 ligand 1	polymer	128	14678.8	6	UniProt (Q9NZQ7) Pfam (PF07686)	Homo sapiens (Human)	hPD-L1,B7 homolog 1,B7-H1
2	G, H, I (A, D, E)	N-(2-((2'-chloro-3'-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-methoxy-[1,1'-biphenyl]-4-yl)(methyl)amino)ethyl)methanesulfonamide	non-polymer		503.0	3	Chemie (UGZ)
3	J, K, L, M, N... (C, A, B, D, E...)	water	water		18.0	42	Chemie (HOH)

Sequence modifications

C, A, B, D, E, F: 18 - 134 (UniProt: Q9NZQ7)

PDB	External Database	Details
Ala 135	-	expression tag
Ala 136	-	expression tag
Ala 137	-	expression tag
Leu 138	-	expression tag
Glu 139	-	expression tag
His 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	88072.6
Non-Polymers*	Number of molecules	3
	Total formula weight	1509.0
All*	Total formula weight	89581.6

*Water molecules are not included.