7NK0

Structure of the BIR1 domain of cIAP2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (D, E)	Baculoviral IAP repeat-containing protein 3	polymer	98	11053.6	2	UniProt (Q13489) Pfam (PF00653)	Homo sapiens (Human)	Apoptosis inhibitor 2,API2,Cellular inhibitor of apoptosis 2,C-IAP2,IAP homolog C,Inhibitor of apoptosis protein 1,hIAP-1,hIAP1,RING finger protein 49,RING-type E3 ubiquitin transferase BIRC3,TNFR2-TRAF-signaling complex protein 1
2	C, D (D, E)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	E, F (D, E)	water	water		18.0	5	Chemie (HOH)

Sequence modifications

D, E: 26 - 102 (UniProt: Q13489)

PDB	External Database	Details
Met 5	-	initiating methionine
Gly 6	-	expression tag
Ser 7	-	expression tag
Ser 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
Ser 15	-	expression tag
Ser 16	-	expression tag
Gly 17	-	expression tag
Leu 18	-	expression tag
Val 19	-	expression tag
Pro 20	-	expression tag
Arg 21	-	expression tag
Gly 22	-	expression tag
Ser 23	-	expression tag
His 24	-	expression tag
Met 25	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	22107.3
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	22238.1

*Water molecules are not included.