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7NIV

Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (phosphatidylcholine-bound, occluded conformation)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(D)
QA2 Fab-fragment light chainpolymer21523258.81Homo sapiens (Human)
2B
(E)
QA2 Fab-fragment light chainpolymer23424817.71Homo sapiens (Human)
3C
(A)
Isoform 2 of Phosphatidylcholine translocator ABCB4polymer1279140835.41UniProt (P21439)
Pfam (PF00664)
Pfam (PF00005)
Homo sapiens (Human)ATP-binding cassette sub-family B member 4,Multidrug resistance protein 3,P-glycoprotein 3
4D
(B)
4B1 Fab-fragment light chainpolymer21523347.01Homo sapiens (Human)
5E
(C)
4B1 Fab-fragment light chainpolymer24125754.61Homo sapiens (Human)
6F
(A)
1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINEnon-polymer782.11Chemie (DLP)
7G, H, I, J, K...
(A)
CHOLESTEROLnon-polymer386.77Chemie (CLR)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight238013.4
Non-Polymers*Number of molecules8
Total formula weight3488.7
All*Total formula weight241502.0
*Water molecules are not included.

246905

PDB entries from 2025-12-31

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