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7NI4

Human ATM kinase domain with bound M4076 inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Serine-protein kinase ATMpolymer3056351127.72UniProt (Q13315)
Pfam (PF11640)
Pfam (PF02259)
Pfam (PF00454)
Pfam (PF02260)
Homo sapiens (Human)Ataxia telangiectasia mutated,A-T mutated
2C, E
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
3D, F
(A, B)
8-(1,3-dimethylpyrazol-4-yl)-1-(3-fluoranyl-5-methoxy-pyridin-4-yl)-7-methoxy-3-methyl-imidazo[4,5-c]quinolin-2-onenon-polymer448.42Chemie (UGK)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight702255.4
Non-Polymers*Number of molecules4
Total formula weight1027.7
All*Total formula weight703283.1
*Water molecules are not included.

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PDB entries from 2026-03-25

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