7NEE
Inhibitor Complex with Thrombin Activatable Fibrinolysis inhibitor (TAFIa)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carboxypeptidase B2 | polymer | 400 | 45933.0 | 1 | UniProt (Q96IY4) Pfam (PF02244) Pfam (PF00246) | Homo sapiens (Human) | Carboxypeptidase U,CPU,Plasma carboxypeptidase B,pCPB,Thrombin-activable fibrinolysis inhibitor,TAFI |
| 2 | B (A) | (1R,3S)-3-(4-ammoniobutyl)-1-benzyl-1,4-azaphosphinan-1-ium-3-carboxylate 4,4-dioxide | non-polymer | 342.4 | 1 | Chemie (U9B) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence modifications
A: 24 - 423 (UniProt: Q96IY4)
| PDB | External Database | Details |
|---|---|---|
| Cys 327 | Ser 327 | conflict |
| Ile 351 | Thr 351 | conflict |
| Tyr 355 | His 355 | conflict |
| Gln 357 | His 357 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45933.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 407.8 | |
| All* | Total formula weight | 46340.8 |
