7NDQ

Gag:02 TCR in complex with HLA-E.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (AAA)	HLA class I histocompatibility antigen, alpha chain E	polymer	277	31955.2	1	UniProt (P13747) Pfam (PF00129) Pfam (PF07654)	Homo sapiens (Human)	MHC class I antigen E
2	B (BBB)	Beta-2-microglobulin	polymer	100	11879.4	1	UniProt (P61769) Pfam (PF07654)	Homo sapiens (Human)
3	C (CCC)	Gag6V	polymer	9	1066.3	1	UniProt (B6S6I4)	Human immunodeficiency virus 1	Gag polyprotein,Matrix protein p17,Nucleocapsid protein p7,Pr55Gag,p6-gag,Capsid protein p24
4	D (DDD)	TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha	polymer	199	22074.5	1	UniProt (A0A0B4J268) UniProt (A0A075B6U7) UniProt (P0DSE1) Pfam (PF07686) Pfam (PF09291)	Homo sapiens (Human)	T cell receptor alpha variable 4,T cell receptor alpha joining 23,TR alpha chain TRAV27*01J42*01C*01, M1-specific T cell receptor alpha chain
5	E (EEE)	T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain	polymer	244	27914.0	1	UniProt (P04435) UniProt (A0A0J9YX06) UniProt (K7N5M4) Pfam (PF07686) Pfam (PF07654)	Homo sapiens (Human)	T cell receptor beta variable 7-9,T cell receptor beta joining 1-2,Human nkt tcr beta chain
6	F, G, H, I (AAA, BBB, DDD, EEE)	water	water		18.0	13	Chemie (HOH)

Sequence modifications

AAA: 1 - 276 (UniProt: P13747)

PDB	External Database	Details
Met 0	-	initiating methionine

BBB: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

DDD: 1 - 107 (UniProt: A0A0B4J268)

PDB	External Database	Details
Met 0	-	initiating methionine
Ser 108	-	linker
Ser 109	-	linker
Phe 110	-	linker

DDD: 111 - 128 (UniProt: A0A075B6U7)

PDB	External Database	Details
Asn 129	-	linker

DDD: 130 - 214 (UniProt: P0DSE1)

PDB	External Database	Details
Cys 176	Thr 175	engineered mutation

EEE: 1 - 108 (UniProt: P04435)

PDB	External Database	Details
Met 0	-	initiating methionine
Gly 109	-	linker
Arg 110	-	linker
Glu 113	-	linker

EEE: 114 - 127 (UniProt: A0A0J9YX06)
EEE: 129 - 258 (UniProt: K7N5M4)

PDB	External Database	Details
Asn 132	Lys 123	engineered mutation
Lys 133	Asn 124	engineered mutation
Asp 217	Asn 208	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	94889.3
All*	Total formula weight	94889.3

*Water molecules are not included.