7NDL
Crystal structure of human GFAT-1 S205D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Isoform 2 of Glutamine-fructose-6-phosphate aminotransferase [isomerizing] 1 | polymer | 686 | 77672.8 | 2 | UniProt (Q06210-2) Pfam (PF13522) Pfam (PF01380) UniProt (by SIFTS) (Q06210) | Homo sapiens (Human) | D-fructose-6-phosphate amidotransferase 1,Glutamine:fructose-6-phosphate amidotransferase 1,GFAT1,Hexosephosphate aminotransferase 1 |
| 2 | C, E (A, B) | GLUCOSE-6-PHOSPHATE | non-polymer | 260.1 | 2 | Chemie (G6Q) | |||
| 3 | D (A) | GLUTAMIC ACID | non-polymer | 147.1 | 1 | Chemie (GLU) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 681 (UniProt: Q06210-2)
| PDB | External Database | Details |
|---|---|---|
| Asp 205 | Ser 205 | engineered mutation |
| His 295 | - | insertion |
| His 295 | - | insertion |
| His 295 | - | insertion |
| His 295 | - | insertion |
| His 295 | - | insertion |
| His 295 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 155345.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 667.4 | |
| All* | Total formula weight | 156013.0 |
