7ND2

Cryo-EM structure of the human FERRY complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protein phosphatase 1 regulatory subunit 21	polymer	784	88782.8	2	UniProt (Q6ZMI0) Pfam (PF10205) Pfam (PF10212) Pfam (PF21636) In PDB	Homo sapiens (Human)	Coiled-coil domain-containing protein 128,KLRAQ motif-containing protein 1
2	C, D	Quinone oxidoreductase-like protein 1	polymer	356	39661.4	2	UniProt (O95825) In PDB	Homo sapiens (Human)	Protein 4P11,Quinone oxidoreductase homolog 1,QOH-1,Zeta-crystallin homolog
3	E, F, H, G	Glutamine amidotransferase-like class 1 domain-containing protein 1	polymer	227	24237.5	4	UniProt (Q8NB37) In PDB	Homo sapiens (Human)	Parkinson disease 7 domain-containing protein 1

Sequence modifications

A, B: 1 - 780 (UniProt: Q6ZMI0)

PDB	External Database	Details
Met -3	-	initiating methionine
Ala -2	-	expression tag
Ala -1	-	expression tag
Ala 0	-	expression tag

C, D: 2 - 349 (UniProt: O95825)

PDB	External Database	Details
Met -6	-	initiating methionine
Ser -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

E, F, H, G: 2 - 220 (UniProt: Q8NB37)

PDB	External Database	Details
Met -6	-	initiating methionine
Ser -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	353838.5
All*	Total formula weight	353838.5

*Water molecules are not included.