7NBS
Crystal structure of SARS-CoV-2 main protease (Mpro) in complex with the HCV NS3/4A inhibitor telaprevir
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AAA) | 3C-like proteinase | polymer | 306 | 33825.5 | 1 | UniProt (P0DTD1) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
| 2 | B (AAA) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 3 | C (AAA) | (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide | non-polymer | 681.9 | 1 | BIRD (PRD_002448) Chemie (SV6) PubChem (23634854) PubChem (59235546) PubChem (59235541) PubChem (59356439) PubChem (68458137) PubChem (68573663) PubChem (70315220) PubChem (70702388) PubChem (70904955) PubChem (89431687) PubChem (89827385) PubChem (101878924) PubChem (117627200) PubChem (58991585) PubChem (59235545) PubChem (59235547) PubChem (59519874) PubChem (70905009) PubChem (74074001) PubChem (78358367) PubChem (78358368) PubChem (78358369) PubChem (117844340) PubChem (117844342) PubChem (117879778) PubChem (142694691) | |||
| 4 | D (AAA) | water | water | 18.0 | 155 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33825.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 717.3 | |
| All* | Total formula weight | 34542.9 |
