7NBI
Crystal structure of a monomeric FLT3 Ligand variant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fms-related tyrosine kinase 3 ligand | polymer | 138 | 15875.1 | 2 | UniProt (P49771) Pfam (PF02947) | Homo sapiens (Human) | Flt3 ligand,Flt3L,SL cytokine |
| 2 | C, D, E, F, G (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | H, I (A, B) | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 134 (UniProt: P49771)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| Asp 27 | Leu 53 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31750.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 480.3 | |
| All* | Total formula weight | 32230.6 |
