7NAL

Cryo-EM structure of activated human SARM1 in complex with NMN and 1AD (ARM and SAM domains)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	NAD(+) hydrolase SARM1	polymer	697	76471.5	8	UniProt (Q6SZW1) Pfam (PF07647) Pfam (PF13676) In PDB	Homo sapiens (Human)	hSARM1,NADP(+) hydrolase SARM1,Sterile alpha and Armadillo repeat protein,Sterile alpha and TIR motif-containing protein 1,Sterile alpha motif domain-containing protein 2,SAM domain-containing protein 2,Tir-1 homolog,HsTIR
2	A, B, C, D, E...	BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE	non-polymer		335.2	8	Chemie (NMN)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	611771.8
Non-Polymers*	Number of molecules	8
	Total formula weight	2681.8
All*	Total formula weight	614453.6

*Water molecules are not included.