7N8G
Crystal structure of R20A-R22A human Galectin-7 mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Galectin-7 | polymer | 135 | 14793.6 | 2 | UniProt (P47929) Pfam (PF00337) | Homo sapiens (Human) | Gal-7,HKL-14,PI7,p53-induced gene 1 protein |
| 2 | C, D, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 3 | E (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 4 | G, H, I, J, K (A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 255 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 135 (UniProt: P47929)
| PDB | External Database | Details |
|---|---|---|
| Ala 20 | Arg 21 | engineered mutation |
| Ala 22 | Arg 23 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29587.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 768.8 | |
| All* | Total formula weight | 30356.1 |
