7N86

Crystal Structure of Human Protocadherin-24 EC1-2 Form II

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Cadherin-related family member 2	polymer	238	26042.3	4	UniProt (Q9BYE9) Pfam (PF00028)	Homo sapiens (Human)	Protocadherin LKC,PC-LKC,Protocadherin-24
2	E, F, G, H (E, F, G, H)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	4	In PDB GlyTouCan (G15407YE)
3	I (A)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
4	BA, CA, DA, EA, J... (D, A, B, C)	CALCIUM ION	non-polymer		40.1	14	Chemie (CA)
5	AA, FA, M, S, Y... (C, D, A, B)	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
6	N, T (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
7	R (B)	IODIDE ION	non-polymer		126.9	1	Chemie (IOD)
8	GA, HA, IA, JA (A, B, C, D)	water	water		18.0	33	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 220 (UniProt: Q9BYE9)

PDB	External Database	Details
Thr 221	-	expression tag
Val 222	-	expression tag
Pro 223	-	expression tag
Arg 224	-	expression tag
Ala 225	-	expression tag
Arg 226	-	expression tag
Asp 227	-	expression tag
Pro 228	-	expression tag
Pro 229	-	expression tag
Val 230	-	expression tag
Gly 231	-	expression tag
Gly 232	-	expression tag
His 233	-	expression tag
His 234	-	expression tag
His 235	-	expression tag
His 236	-	expression tag
His 237	-	expression tag
His 238	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	104169.4
Branched	Number of molecules	4
	Total formula weight	2346.2
Non-Polymers*	Number of molecules	24
	Total formula weight	1068.8
All*	Total formula weight	107584.4

*Water molecules are not included.