7N72

Cryo-EM structure of ATP13A2 in the AlF-bound E2-Pi-like state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Isoform 3 of Polyamine-transporting ATPase 13A2	polymer	1175	128444.5	1	UniProt (Q9NQ11) Pfam (PF12409) Pfam (PF00122) Pfam (PF13246)	Homo sapiens (Human)
2	B (A)	TETRAFLUOROALUMINATE ION	non-polymer		103.0	1	Chemie (ALF) PubChem (5311325)
3	C (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
4	D (A)	SPERMINE	non-polymer		202.3	1	Chemie (SPM) PubChem (1103)
5	E, F, L (A)	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	3	Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (65082) PubChem (45489984) PubChem (363416) PubChem (60078761) PubChem (500055) PubChem (73440805) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (99567469) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (13301926) PubChem (13301927) PubChem (124914595) PubChem (124914596) PubChem (155804219) PubChem (169132514) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028)
6	G, K (A)	1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		790.1	2	Chemie (PC1) PubChem (65146) PubChem (94190) PubChem (10417837)
7	H, I, J (A)	DODECYL-BETA-D-MALTOSIDE	non-polymer		510.6	3	Chemie (LMT)
8	M (A)	water	water		18.0	5	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	128444.5
Non-Polymers*	Number of molecules	11
	Total formula weight	4901.9
All*	Total formula weight	133346.4

*Water molecules are not included.