7N5P
6218 TCR in complex with H2-Db PA224-233 with a cysteine mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | H-2 class I histocompatibility antigen, D-B alpha chain | polymer | 277 | 32184.8 | 1 | UniProt (P01899) Pfam (PF00129) Pfam (PF07654) In PDB | Mus musculus (Mouse) | H-2D(B) |
2 | B | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
3 | C | peptide from Polymerase acidic protein | polymer | 10 | 1160.3 | 1 | UniProt (O89752) In PDB | Influenza A virus | RNA-directed RNA polymerase subunit P2 |
4 | D | Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain | polymer | 204 | 22494.8 | 1 | UniProt (A0A075B6C4) UniProt (K7N5N2) Pfam (PF07686) Pfam (PF09291) In PDB | Mus musculus (Mouse) | T-cell receptor,sp3.4 beta chain |
5 | E | Fusion protein of T cell receptor beta, variable 29 and Human nkt tcr beta chain | polymer | 240 | 27575.9 | 1 | UniProt (A0A0G2LB96) UniProt (K7N5M4) Pfam (PF07686) Pfam (PF07654) In PDB | Mus musculus (Mouse) | |
6 | D, E | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
7 | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
B: 1 - 99 (UniProt: P61769)
C: 1 - 10 (UniProt: O89752)
D: 1 - 106 (UniProt: A0A075B6C4)
D: 128 - 220 (UniProt: K7N5N2)
E: 1 - 107 (UniProt: A0A0G2LB96)
E: 111 - 253 (UniProt: K7N5M4)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
PDB | External Database | Details |
---|---|---|
Cys 4 | Glu 227 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 107 | - | linker |
Gly 108 | - | linker |
Gly 109 | - | linker |
Ser 110 | - | linker |
Asn 111 | - | linker |
Tyr 112 | - | linker |
Lys 113 | - | linker |
Leu 114 | - | linker |
Thr 115 | - | linker |
Phe 116 | - | linker |
Gly 117 | - | linker |
Lys 118 | - | linker |
Gly 119 | - | linker |
Thr 120 | - | linker |
Leu 121 | - | linker |
Leu 122 | - | linker |
Thr 123 | - | linker |
Val 124 | - | linker |
Thr 125 | - | linker |
Pro 126 | - | linker |
Asn 127 | - | linker |
E: 1 - 107 (UniProt: A0A0G2LB96)
PDB | External Database | Details |
---|---|---|
Phe 108 | - | linker |
Gly 109 | - | linker |
Arg 110 | - | linker |
PDB | External Database | Details |
---|---|---|
Leu 123 | Thr 119 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 95295.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 92.0 | |
All* | Total formula weight | 95387.2 |