7N3M

Co-complex CYP46A1 with 0431 (compound 17)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	AAA	Cholesterol 24-hydroxylase	polymer	474	54434.7	1	UniProt (Q9Y6A2) Pfam (PF00067) In PDB	Homo sapiens (Human)	CH24H,Cholesterol 24-monooxygenase,Cholesterol 24S-hydroxylase,Cytochrome P450 46A1
2	AAA	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	1	Chemie (HEM)
3	AAA	N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)pyridin-3-yl]piperidine-4-carboxamide	non-polymer		313.4	1	Chemie (05D)
4		water	water		18.0	390	Chemie (HOH)

Sequence modifications

AAA: 28 - 494 (UniProt: Q9Y6A2)

PDB	External Database	Details
Met 21	-	initiating methionine
His 22	-	expression tag
His 23	-	expression tag
His 24	-	expression tag
His 25	-	expression tag
His 26	-	expression tag
His 27	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	54434.7
Non-Polymers*	Number of molecules	2
	Total formula weight	929.9
All*	Total formula weight	55364.6

*Water molecules are not included.