7N3M

Co-complex CYP46A1 with 0431 (compound 17)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0004497	molecular_function	monooxygenase activity
AAA	0005506	molecular_function	iron ion binding
AAA	0005783	cellular_component	endoplasmic reticulum
AAA	0005789	cellular_component	endoplasmic reticulum membrane
AAA	0006699	biological_process	bile acid biosynthetic process
AAA	0006707	biological_process	cholesterol catabolic process
AAA	0006805	biological_process	xenobiotic metabolic process
AAA	0007399	biological_process	nervous system development
AAA	0008203	biological_process	cholesterol metabolic process
AAA	0008207	biological_process	C21-steroid hormone metabolic process
AAA	0008395	molecular_function	steroid hydroxylase activity
AAA	0016020	cellular_component	membrane
AAA	0016125	biological_process	sterol metabolic process
AAA	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
AAA	0020037	molecular_function	heme binding
AAA	0030425	cellular_component	dendrite
AAA	0033781	molecular_function	cholesterol 24-hydroxylase activity
AAA	0042448	biological_process	progesterone metabolic process
AAA	0042995	cellular_component	cell projection
AAA	0045202	cellular_component	synapse
AAA	0046872	molecular_function	metal ion binding
AAA	0062184	molecular_function	testosterone 16-beta-hydroxylase activity
AAA	0098793	cellular_component	presynapse
AAA	0098794	cellular_component	postsynapse
AAA	1900271	biological_process	regulation of long-term synaptic potentiation
AAA	1903044	biological_process	protein localization to membrane raft

Functional Information from PROSITE/UniProt

site_id	PS00086
Number of Residues	10
Details	CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FSlGHRSCIG

Chain	Residue	Details
AAA	PHE430-GLY439

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: axial binding residue => ECO:0000269|PubMed:18621681, ECO:0000269|PubMed:20667828, ECO:0000269|PubMed:23288837, ECO:0007744|PDB:2Q9F, ECO:0007744|PDB:2Q9G, ECO:0007744|PDB:3MDR, ECO:0007744|PDB:3MDT, ECO:0007744|PDB:3MDV, ECO:0007744|PDB:4ENH, ECO:0007744|PDB:4FIA, ECO:0007744|PDB:4J14

Chain	Residue	Details
AAA	CYS437

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