7N1O
The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcription factor ETV6,Isoform 4 of Anthrax toxin receptor 2 | polymer | 257 | 28647.7 | 1 | UniProt (P41212) UniProt (P58335) Pfam (PF02198) Pfam (PF00092) | Homo sapiens (Human) | ETS translocation variant 6,ETS-related protein Tel1,Tel,Capillary morphogenesis gene 2 protein,CMG-2 |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C, D (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | E (A) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 1 - 78 (UniProt: P41212)
A: 80 - 257 (UniProt: P58335)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | Asp 46 | engineered mutation |
| Ala 4 | Arg 49 | engineered mutation |
| Glu 67 | Val 112 | engineered mutation |
| Ala 77 | Lys 122 | engineered mutation |
| Ala 79 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 81 | Arg 41 | engineered mutation |
| Ala 215 | Cys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28647.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 95.2 | |
| All* | Total formula weight | 28742.9 |
