7N13
Crystal structure of MTH1 in complex with compound 32
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 7,8-dihydro-8-oxoguanine triphosphatase | polymer | 158 | 18115.6 | 2 | UniProt (P36639) Pfam (PF00293) | Homo sapiens (Human) | 2-hydroxy-dATP diphosphatase,8-oxo-dGTPase,Nucleoside diphosphate-linked moiety X motif 1,Nudix motif 1 |
| 2 | C, F (A, B) | 4-anilino-6-[4-(butylcarbamoyl)-3-fluorophenyl]-N-cyclopropyl-7-fluoroquinoline-3-carboxamide | non-polymer | 514.6 | 2 | Chemie (ZRV) | |||
| 3 | D, E, G, H, I... (A, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | K, L (A, B) | water | water | 18.0 | 302 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 156 (UniProt: P36639)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36231.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1605.5 | |
| All* | Total formula weight | 37836.7 |
