7N12
Crystal structure of the M. abscessus LeuRS editing domain in complex with epetraborole-AMP adduct
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Leucine--tRNA ligase | polymer | 196 | 21024.3 | 2 | UniProt (A0A0U0XQP3) | Mycobacteroides abscessus | Leucyl-tRNA synthetase,LeuRS |
| 2 | C, E (B, A) | [(1S,5R,6R,7'S,8R)-7'-(aminomethyl)-6-(6-aminopurin-9-yl)-2'-(3-oxidanylpropoxy)spiro[2,4,7-trioxa-3-boranuidabicyclo[3.3.0]octane-3,9'-8-oxa-9-boranuidabicyclo[4.3.0]nona-1(6),2,4-triene]-8-yl]methyl dihydrogen phosphate | non-polymer | 565.3 | 2 | Chemie (365) | |||
| 3 | D (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G (B, A) | water | water | 18.0 | 384 | Chemie (HOH) |
Sequence modifications
B, A: 303 - 498 (UniProt: A0A0U0XQP3)
| PDB | External Database | Details |
|---|---|---|
| Ala 315 | Val 315 | conflict |
| Thr 355 | Ala 355 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42048.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1226.6 | |
| All* | Total formula weight | 43275.1 |
