7N12
Crystal structure of the M. abscessus LeuRS editing domain in complex with epetraborole-AMP adduct
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002161 | molecular_function | aminoacyl-tRNA deacylase activity |
| A | 0004823 | molecular_function | leucine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006429 | biological_process | leucyl-tRNA aminoacylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0002161 | molecular_function | aminoacyl-tRNA deacylase activity |
| B | 0004823 | molecular_function | leucine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006429 | biological_process | leucyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue 365 B 501 |
| Chain | Residue |
| B | PHE321 |
| B | MET427 |
| B | VAL429 |
| B | HIS432 |
| B | ASP433 |
| B | ARG435 |
| B | ASP436 |
| B | HOH673 |
| B | HOH685 |
| B | HOH690 |
| B | HOH704 |
| B | THR322 |
| B | THR323 |
| B | ARG324 |
| B | TYR416 |
| B | VAL417 |
| B | LEU418 |
| B | TYR421 |
| B | ILE426 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 502 |
| Chain | Residue |
| A | ARG375 |
| A | HOH617 |
| B | TYR472 |
| B | ARG488 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue 365 A 501 |
| Chain | Residue |
| A | PHE321 |
| A | THR322 |
| A | THR323 |
| A | ARG324 |
| A | TYR416 |
| A | VAL417 |
| A | LEU418 |
| A | TYR421 |
| A | ILE426 |
| A | MET427 |
| A | VAL429 |
| A | HIS432 |
| A | ASP433 |
| A | ARG435 |
| A | ASP436 |
| A | HOH603 |
| A | HOH680 |
| A | HOH685 |
| A | HOH701 |
