7N09

Structural basis for branched substrate selectivity in a ketoreductase from Ascaris suum

Replaces:  6U5I

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	3-hydroxyacyl-CoA dehydrogenase type-2	polymer	277	29365.9	2	UniProt (F1L0H2) Pfam (PF00106)	Ascaris suum (Pig roundworm)
2	C, D (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	E, F (A, B)	water	water		18.0	375	Chemie (HOH)

Sequence modifications

A, B: 2 - 260 (UniProt: F1L0H2)

PDB	External Database	Details
Met -16	-	initiating methionine
Ala -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Leu -6	-	expression tag
Glu -5	-	expression tag
Val -4	-	expression tag
Leu -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
Pro 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58731.7
Non-Polymers*	Number of molecules	2
	Total formula weight	1326.8
All*	Total formula weight	60058.6

*Water molecules are not included.