7N09

Structural basis for branched substrate selectivity in a ketoreductase from Ascaris suum

Replaces:  6U5I

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003857	molecular_function	(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
A	0004303	molecular_function	estradiol 17-beta-dehydrogenase [NAD(P)+] activity
A	0005739	cellular_component	mitochondrion
A	0006631	biological_process	fatty acid metabolic process
A	0008209	biological_process	androgen metabolic process
A	0008210	biological_process	estrogen metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0047044	molecular_function	androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity
B	0000166	molecular_function	nucleotide binding
B	0003857	molecular_function	(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
B	0004303	molecular_function	estradiol 17-beta-dehydrogenase [NAD(P)+] activity
B	0005739	cellular_component	mitochondrion
B	0006631	biological_process	fatty acid metabolic process
B	0008209	biological_process	androgen metabolic process
B	0008210	biological_process	estrogen metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0047044	molecular_function	androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity

Functional Information from PROSITE/UniProt

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. SiaafdgqagQsaYSASKGAIvGMTlPLA

Chain	Residue	Details
A	SER154-ALA182

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