7N00
Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 648-1025 in complex with AUG-alpha
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | ALK tyrosine kinase receptor | polymer | 379 | 39377.6 | 2 | UniProt (Q9UM73) Pfam (PF12810) In PDB | Homo sapiens (Human) | Anaplastic lymphoma kinase |
2 | B, D | ALK and LTK ligand 2 | polymer | 128 | 14640.0 | 2 | UniProt (Q6UX46) Pfam (PF15129) In PDB | Homo sapiens (Human) | Augmentor alpha,AUG-alpha,Protein FAM150B |
Sequence modifications
A, C: 648 - 1025 (UniProt: Q9UM73)
B, D: 25 - 152 (UniProt: Q6UX46)
PDB | External Database | Details |
---|---|---|
Gly 647 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Tyr 66 | Cys 66 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 108035.1 | |
All* | Total formula weight | 108035.1 |