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7MZ8

Structure of human DNA polymerase beta complexed with 3-deaza-3-methyladenine (3dMeA) at N-1 of the template base paired with incoming dTTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA polymerase betapolymer32937536.81UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
In PDB
Homo sapiens (Human)
2TDNA (5'-D(*CP*CP*GP*AP*CP*GP*(DZM)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')polymer164866.21Homo sapiens
3PDNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-3')polymer103076.01Homo sapiens
4DDNA (5'-D(P*GP*TP*CP*GP*G)-3')polymer51536.01Homo sapiens
5AMAGNESIUM IONnon-polymer24.31Chemie (MG)
6ASODIUM IONnon-polymer23.02Chemie (NA)
7A2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidinenon-polymer466.21Chemie (0KX)
8waterwater18.068Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47015.0
Non-Polymers*Number of molecules4
Total formula weight536.5
All*Total formula weight47551.5
*Water molecules are not included.

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PDB entries from 2024-07-17

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