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7MZ2

Structure of human DNA polymerase beta complexed with dzA at N-1 of the template base paired with incoming dTTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer32637182.41UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)
2B
(T)
DNA (5'-D(*CP*CP*GP*AP*CP*GP*(4DU)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')polymer164852.21Homo sapiens
3C
(P)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-3')polymer103076.01Homo sapiens
4D
(D)
DNA (5'-D(P*GP*TP*CP*GP*G)-3')polymer51536.01Homo sapiens
5E, F
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6G, H
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
7I
(A)
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidinenon-polymer466.21Chemie (0KX)
8J, K, L, M
(A, T, P, D)
waterwater18.0146Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight46646.6
Non-Polymers*Number of molecules5
Total formula weight560.8
All*Total formula weight47207.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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