7MYL
Crystal structure of DfrA1 dihydrofolate reductase in complex with TRIMETHOPRIM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Dihydrofolate reductase | polymer | 161 | 18110.6 | 6 | UniProt (A4GRC7) Pfam (PF00186) In PDB | Klebsiella pneumoniae | |
| 2 | A, B, C, D, E... | TRIMETHOPRIM | non-polymer | 290.3 | 6 | Chemie (TOP) | |||
| 3 | water | water | 18.0 | 49 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 157 (UniProt: A4GRC7)
| PDB | External Database | Details |
|---|---|---|
| Leu 158 | - | expression tag |
| Glu 159 | - | expression tag |
| His 160 | - | expression tag |
| His 161 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 108663.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1741.9 | |
| All* | Total formula weight | 110405.4 |
