7MYL

Crystal structure of DfrA1 dihydrofolate reductase in complex with TRIMETHOPRIM

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Dihydrofolate reductase	polymer	161	18110.6	6	UniProt (A4GRC7)	Klebsiella pneumoniae
2	G, H, I, J, K... (A, B, C, D, E...)	TRIMETHOPRIM	non-polymer		290.3	6	Chemie (TOP)
3	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	49	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 157 (UniProt: A4GRC7)

PDB	External Database	Details
Leu 158	-	expression tag
Glu 159	-	expression tag
His 160	-	expression tag
His 161	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	108663.5
Non-Polymers*	Number of molecules	6
	Total formula weight	1741.9
All*	Total formula weight	110405.4

*Water molecules are not included.