7MXF
CD1c with antigen analogue 2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | T-cell surface glycoprotein CD1c, T-cell surface glycoprotein CD1b chimeric protein | polymer | 285 | 31998.8 | 1 | UniProt (P29017) UniProt (P29016) Pfam (PF16497) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
2 | B | Beta-2-microglobulin | polymer | 108 | 12616.1 | 1 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
4 | A | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID | non-polymer | 207.3 | 1 | Chemie (NHE) | |||
5 | A | 2,6-anhydro-1-deoxy-1-[(S)-hydroxy{[(4R,8S,12R,16R,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-D-glycero-D-galacto-heptitol | non-polymer | 707.0 | 1 | Chemie (ZQ4) | |||
6 | A | DODECANE | non-polymer | 170.3 | 1 | Chemie (D12) | |||
7 | A | (2S)-2,3-dihydroxypropyl hexadecanoate | non-polymer | 330.5 | 1 | Chemie (ZP7) | |||
8 | B | MALONIC ACID | non-polymer | 104.1 | 1 | Chemie (MLA) | |||
9 | water | water | 18.0 | 137 | Chemie (HOH) |
Sequence modifications
A: 1 - 194 (UniProt: P29017)
A: 195 - 279 (UniProt: P29016)
B: 1 - 100 (UniProt: P61769)
PDB | External Database | Details |
---|---|---|
Gln 52 | Asn 70 | engineered mutation |
Gln 57 | Asn 75 | engineered mutation |
Gly 108 | Lys 126 | engineered mutation |
Gln 128 | Asn 146 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 242 | Trp 259 | engineered mutation |
Gly 280 | - | expression tag |
Ser 281 | - | expression tag |
Leu 282 | - | expression tag |
Val 283 | - | expression tag |
Pro 284 | - | expression tag |
Arg 285 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Asp -1 | - | expression tag |
Ala 0 | - | expression tag |
Gly 101 | - | expression tag |
Ser 102 | - | expression tag |
Leu 103 | - | expression tag |
Val 104 | - | expression tag |
Pro 105 | - | expression tag |
Arg 106 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 44614.9 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1740.4 | |
All* | Total formula weight | 46355.3 |