7MWM
Crystal structure of MBD2 with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Methyl-CpG-binding domain protein 2 | polymer | 79 | 8763.2 | 2 | UniProt (Q9UBB5) Pfam (PF01429) | Homo sapiens (Human) | Demethylase,DMTase,Methyl-CpG-binding protein MBD2 |
| 2 | C, D, E, F (C, D, E, F) | DNA (5'-D(*GP*CP*CP*AP*A)-R(P*(5MC))-D(P*GP*TP*TP*GP*GP*C)-3') | polymer | 12 | 3677.4 | 4 | synthetic construct | ||
| 3 | AA, BA, CA, DA, EA... (B, C, A, D, E...) | UNKNOWN ATOM OR ION | non-polymer | 35 | Chemie (UNX) | ||||
| 4 | PA, QA, RA, SA, TA... (A, B, C, D, E...) | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence modifications
A, B: 143 - 220 (UniProt: Q9UBB5)
| PDB | External Database | Details |
|---|---|---|
| Gly 142 | - | expression tag |
| Lys 166 | Arg 166 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 32236.0 | |
| Non-Polymers* | Number of molecules | 35 |
| Total formula weight | 0.0 | |
| All* | Total formula weight | 32236.0 |
