7MVS
DNA gyrase complexed with uncleaved DNA and Compound 7 to 2.6A resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | DNA gyrase subunit B,DNA gyrase subunit A | polymer | 693 | 78166.1 | 2 | UniProt (P0A0K8) UniProt (Q99XG5) Pfam (PF01751) Pfam (PF00986) Pfam (PF00521) UniProt (by SIFTS) (P20831) In PDB | Staphylococcus aureus | |
2 | C, D | DNA (5'-D(P*AP*GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3') | polymer | 20 | 6136.0 | 2 | synthetic construct | ||
3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
4 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
5 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
6 | D | (1S)-2-[(2r,5S)-5-{[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]amino}-1,3-dioxan-2-yl]-1-(3-fluoro-6-methoxyquinolin-4-yl)ethan-1-ol | non-polymer | 470.5 | 1 | Chemie (Y1W) | |||
7 | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 136 (UniProt: P0A0K8)
A, B: 139 - 199 (UniProt: P0A0K8)
A, B: 199 - 692 (UniProt: Q99XG5)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
Met 2 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Thr 137 | - | linker |
Gly 138 | - | linker |
PDB | External Database | Details |
---|---|---|
Phe 324 | Tyr 123 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 168604.0 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 782.8 | |
All* | Total formula weight | 169386.8 |