7MU3
human carbonic anhydrase 9 mimic with compound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic anhydrase 2 | polymer | 260 | 29226.9 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | ethyl (8R)-7-methyl-3-({[(4-sulfamoylphenyl)methyl]carbamothioyl}amino)pyrazolo[1,5-a]pyrimidine-6-carboxylate | non-polymer | 448.5 | 1 | Chemie (ZOA) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 6 | F, G, H (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | I (A) | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
A: 1 - 261 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Ser 65 | Ala 65 | conflict |
| Gln 67 | Asn 67 | conflict |
| Thr 69 | Glu 69 | conflict |
| Leu 91 | Ile 91 | conflict |
| Val 131 | Phe 130 | conflict |
| Asp 132 | Gly 131 | conflict |
| Leu 135 | Val 134 | conflict |
| Glu 170 | Lys 169 | conflict |
| Ala 204 | Leu 203 | conflict |
| Gly 206 | Cys 205 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29226.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 963.3 | |
| All* | Total formula weight | 30190.2 |
