7MU3
human carbonic anhydrase 9 mimic with compound
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Carbonic anhydrase 2 | polymer | 260 | 29226.9 | 1 | UniProt (P00918) Pfam (PF00194) In PDB | Homo sapiens (Human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | ethyl (8R)-7-methyl-3-({[(4-sulfamoylphenyl)methyl]carbamothioyl}amino)pyrazolo[1,5-a]pyrimidine-6-carboxylate | non-polymer | 448.5 | 1 | Chemie (ZOA) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | A | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
6 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
7 | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
A: 1 - 261 (UniProt: P00918)
PDB | External Database | Details |
---|---|---|
Ser 65 | Ala 65 | conflict |
Gln 67 | Asn 67 | conflict |
Thr 69 | Glu 69 | conflict |
Leu 91 | Ile 91 | conflict |
Val 131 | Phe 130 | conflict |
Asp 132 | Gly 131 | conflict |
Leu 135 | Val 134 | conflict |
Glu 170 | Lys 169 | conflict |
Ala 204 | Leu 203 | conflict |
Gly 206 | Cys 205 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29226.9 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 963.3 | |
All* | Total formula weight | 30190.2 |