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7MTR

CryoEM Structure of Full-Length mGlu2 Bound to Ago-PAM ADX55164 and Glutamate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(B, A)
Metabotropic glutamate receptor 2polymer85593932.42UniProt (Q14416)
Pfam (PF01094)
Pfam (PF07562)
Pfam (PF00003)
Homo sapiens (Human)mGluR2
2C, E
(B, A)
GLUTAMIC ACIDnon-polymer147.12Chemie (GLU)
3D, F
(B, A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
4G
(A)
2-methoxy-6-propyl-N-(2-{4-[(1H-tetrazol-5-yl)methoxy]phenyl}ethyl)thieno[2,3-d]pyrimidin-4-aminenon-polymer425.51Chemie (ZQY)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight187864.9
Non-Polymers*Number of molecules5
Total formula weight1162.2
All*Total formula weight189027.1
*Water molecules are not included.

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PDB entries from 2025-12-24

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