7MSO
Crystal Structure of Polo Box Domain in Complex with Cyclic Peptide Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase PLK1 | polymer | 237 | 27285.2 | 2 | UniProt (P53350) Pfam (PF00659) | Homo sapiens (Human) | Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13 |
| 2 | C, D (E, F) | Cyclic Peptide Inhibitor ZO1-GLN-SER-TPO-45W-MLL | polymer | 6 | 854.8 | 2 | BIRD (PRD_002479) | synthetic construct | |
| 3 | E, F, G, H (A, B, E, F) | water | water | 18.0 | 328 | Chemie (HOH) |
Sequence modifications
A, B: 371 - 603 (UniProt: P53350)
| PDB | External Database | Details |
|---|---|---|
| Gly 367 | - | expression tag |
| Ala 368 | - | expression tag |
| His 369 | - | expression tag |
| Met 370 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56279.8 | |
| All* | Total formula weight | 56279.8 |
