7MSD
Structure of EED bound to EEDi-6068
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Polycomb protein EED | polymer | 368 | 42412.2 | 1 | UniProt (O75530) Pfam (PF00400) In PDB | Homo sapiens (Human) | hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
2 | A | (9aP,12aR)-4-(2,2-difluoropropyl)-12-{[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]amino}-7-(trifluoromethyl)-4,5-dihydro-3H-2,4,8,11,12a-pentaazabenzo[4,5]cycloocta[1,2,3-cd]inden-3-one | non-polymer | 562.5 | 1 | Chemie (ZMY) | |||
3 | A | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
4 | water | water | 18.0 | 213 | Chemie (HOH) |
Sequence modifications
A: 77 - 441 (UniProt: O75530)
PDB | External Database | Details |
---|---|---|
Ser 74 | - | expression tag |
Asn 75 | - | expression tag |
Ala 76 | - | expression tag |
Thr 370 | Met 370 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42412.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 608.5 | |
All* | Total formula weight | 43020.7 |