7MPH
GRB2 SH2 Domain with Compound 7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Growth factor receptor-bound protein 2 | polymer | 95 | 11008.4 | 6 | UniProt (P62993) Pfam (PF00017) | Homo sapiens (Human) | Adapter protein GRB2,Protein Ash,SH2/SH3 adapter GRB2 |
| 2 | CA, FA, G, L, R... (E, F, A, B, C...) | (4-{(10R,11E,14S,18S)-18-(2-amino-2-oxoethyl)-14-[(naphthalen-1-yl)methyl]-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-10-yl}phenyl)acetic acid | non-polymer | 652.8 | 6 | Chemie (ZLY) | |||
| 3 | DA, EA, GA, H, HA... (E, F, A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 13 | Chemie (EDO) | |||
| 4 | AA, BA, I, J, K... (D, A, B, C) | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
| 5 | KA, LA, MA, NA, OA... (A, B, C, D, E...) | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 59 - 152 (UniProt: P62993)
| PDB | External Database | Details |
|---|---|---|
| Gly 58 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 66050.6 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 5780.3 | |
| All* | Total formula weight | 71830.9 |
