7MO3
Crystal Structure of the ZnF3 of Nucleoporin NUP153 in complex with Ran-GDP, resolution 2.05 Angstrom
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | GTP-binding nuclear protein Ran | polymer | 217 | 24483.1 | 2 | UniProt (P62826) Pfam (PF00071) | Homo sapiens (Human) | Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein |
| 2 | B, D (B, D) | Nuclear pore complex protein Nup153 | polymer | 42 | 4455.1 | 2 | UniProt (P49791) Pfam (PF00641) | Rattus norvegicus (Rat) | 153 kDa nucleoporin,Nucleoporin Nup153 |
| 3 | E, H (A, C) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 4 | F, I (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | G, J (B, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | K, L, M (A, B, C) | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 216 (UniProt: P62826)
B, D: 781 - 817 (UniProt: P49791)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Ser 35 | Phe 35 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 776 | - | expression tag |
| Pro 777 | - | expression tag |
| Leu 778 | - | expression tag |
| Gly 779 | - | expression tag |
| Ser 780 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57876.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1065.8 | |
| All* | Total formula weight | 58942.1 |
