7MO2

Crystal Structure of the ZnF2 of Nucleoporin NUP153 in complex with Ran-GDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	GTP-binding nuclear protein Ran	polymer	217	24483.1	2	UniProt (P62826) Pfam (PF00071)	Homo sapiens (Human)	Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein
2	B, D (B, D)	Nuclear pore complex protein Nup153	polymer	42	4414.1	2	UniProt (P49791) Pfam (PF00641)	Rattus norvegicus (Rat)	153 kDa nucleoporin,Nucleoporin Nup153
3	E, H (A, C)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
4	F, I (A, C)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	G, J (B, D)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
6	K, L, M, N (A, B, C, D)	water	water		18.0	421	Chemie (HOH)

Sequence modifications

A, C: 1 - 216 (UniProt: P62826)

PDB	External Database	Details
Ser 0	-	expression tag
Ser 35	Phe 35	engineered mutation

B, D: 713 - 749 (UniProt: P49791)

PDB	External Database	Details
Gly 708	-	expression tag
Pro 709	-	expression tag
Leu 710	-	expression tag
Gly 711	-	expression tag
Ser 712	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	57794.3
Non-Polymers*	Number of molecules	6
	Total formula weight	1065.8
All*	Total formula weight	58860.2

*Water molecules are not included.