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7MO1

Crystal Structure of the ZnF1 of Nucleoporin NUP153 in complex with Ran-GDP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GTP-binding nuclear protein Ranpolymer21724483.11UniProt (P62826)
Pfam (PF00071)
Homo sapiens (Human)Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein
2B
(B)
Nuclear pore complex protein Nup153polymer444573.21UniProt (P49791)
Pfam (PF00641)
Rattus norvegicus (Rat)153 kDa nucleoporin,Nucleoporin Nup153
3C
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
4D
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5E
(B)
ZINC IONnon-polymer65.41Chemie (ZN)
6F, G
(A, B)
waterwater18.0222Chemie (HOH)
Sequence modifications
A: 1 - 216 (UniProt: P62826)
PDBExternal DatabaseDetails
Ser 0-expression tag
Ser 35Phe 35engineered mutation
B: 648 - 687 (UniProt: P49791)
PDBExternal DatabaseDetails
Gly 644-expression tag
Pro 645-expression tag
Leu 646-expression tag
Gly 647-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight29056.3
Non-Polymers*Number of molecules3
Total formula weight532.9
All*Total formula weight29589.2
*Water molecules are not included.

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PDB entries from 2024-10-30

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