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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7ML4

RNA polymerase II initially transcribing complex (ITC)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1QTranscription initiation factor IIF subunit alphapolymer73582320.61UniProt (P41895)
Pfam (PF05793)
In PDB		Saccharomyces cerevisiae (baker's yeast)TFIIF-alpha,TFIIF large subunit,Transcription factor G 105 kDa subunit,P105
2RTranscription initiation factor IIF subunit betapolymer39846512.41UniProt (A0A6A5PZ00)
Pfam (PF17683)
Pfam (PF02270)
UniProt (by SIFTS) (P41896)
In PDB		Saccharomyces cerevisiae (baker's yeast)
3DDNA-directed RNA polymerase II subunit RPB4polymer22125451.21UniProt (A0A6A5PTI6)
Pfam (PF03874)
UniProt (by SIFTS) (P20433)
In PDB		Saccharomyces cerevisiae (baker's yeast)
4GDNA-directed RNA polymerase II subunit RPB7polymer17119081.11UniProt (A0A6A5Q270)
Pfam (PF03876)
Pfam (PF00575)
UniProt (by SIFTS) (P34087)
In PDB		Saccharomyces cerevisiae (baker's yeast)
5MTranscription initiation factor IIBpolymer34538257.31UniProt (P29055)
Pfam (PF08271)
Pfam (PF00382)
In PDB		Saccharomyces cerevisiae (baker's yeast)General transcription factor TFIIB,Transcription factor E
6ADNA-directed RNA polymerase subunitpolymer1733191821.61UniProt (A0A6A5Q1P2)
Pfam (PF04997)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Pfam (PF04992)
Pfam (PF04990)
Pfam (PF05001)
UniProt (by SIFTS) (P04050)
In PDB		Saccharomyces cerevisiae (baker's yeast)
7BDNA-directed RNA polymerase subunit betapolymer1224138937.31UniProt (A0A6A5Q4H2)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF04566)
Pfam (PF04567)
Pfam (PF00562)
Pfam (PF04560)
UniProt (by SIFTS) (P08518)
In PDB		Saccharomyces cerevisiae (baker's yeast)
8CDNA-directed RNA polymerase II subunit RPB3polymer31835330.51UniProt (A0A6A5Q0Z3)
Pfam (PF01193)
Pfam (PF01000)
UniProt (by SIFTS) (P16370)
In PDB		Saccharomyces cerevisiae (baker's yeast)
9EDNA-directed RNA polymerases I, II, and III subunit RPABC1polymer21525117.11UniProt (A0A6A5Q456)
Pfam (PF03871)
Pfam (PF01191)
UniProt (by SIFTS) (P20434)
In PDB		Saccharomyces cerevisiae (baker's yeast)
10FDNA-directed RNA polymerases I,II,and III subunit RPABC2polymer15517931.81UniProt (A0A6L0ZRI7)
Pfam (PF01192)
UniProt (by SIFTS) (P20435)
In PDB		Saccharomyces cerevisiae (baker's yeast)
11HDNA-directed RNA polymerases I, II, and III subunit RPABC3polymer14616525.41UniProt (A0A6A5Q8C2)
Pfam (PF03870)
UniProt (by SIFTS) (P20436)
In PDB		Saccharomyces cerevisiae (baker's yeast)
12IDNA-directed RNA polymerase II subunit RPB9polymer12214308.21UniProt (A0A7I9EWC2)
Pfam (PF02150)
Pfam (PF01096)
UniProt (by SIFTS) (P27999)
In PDB		Saccharomyces cerevisiae (baker's yeast)
13JDNA-directed RNA polymerases II subunit RPABC5polymer708290.71UniProt (A0A6A5Q7Q6)
Pfam (PF01194)
UniProt (by SIFTS) (P22139)
In PDB		Saccharomyces cerevisiae (baker's yeast)
14KDNA-directed RNA polymerase II subunit RPB11polymer12013633.51UniProt (A0A6A5Q7A1)
Pfam (PF13656)
UniProt (by SIFTS) (P38902)
In PDB		Saccharomyces cerevisiae (baker's yeast)
15LDNA-directed RNA polymerases II subunit RPABC4polymer707730.01UniProt (A0A6A5PY05)
Pfam (PF03604)
UniProt (by SIFTS) (P40422)
In PDB		Saccharomyces cerevisiae (baker's yeast)
163BJ4_G0050160.mRNA.1.CDS.1polymer32138188.41UniProt (A0A7I9BTI9)
Pfam (PF06391)
Pfam (PF17121)
UniProt (by SIFTS) (Q03290)
In PDB		Saccharomyces cerevisiae (baker's yeast)SX2_G0047880.mRNA.1.CDS.1,Y55_G0047830.mRNA.1.CDS.1
170General transcription and DNA repair factor IIH helicase subunit XPDpolymer77889899.01UniProt (A0A6A5Q1C1)
Pfam (PF06733)
Pfam (PF06777)
Pfam (PF13307)
UniProt (by SIFTS) (P06839)
In PDB		Saccharomyces cerevisiae (baker's yeast)
184General transcription and DNA repair factor IIH subunit TFB4polymer33837430.31UniProt (A0A7I9C5C2)
Pfam (PF03850)
UniProt (by SIFTS) (Q12004)
In PDB		Saccharomyces cerevisiae (baker's yeast)RNA polymerase II transcription factor B subunit 4
196General transcription and DNA repair factor IIHpolymer46152024.71UniProt (A0A7I9FQL5)
Pfam (PF04056)
Pfam (PF07975)
UniProt (by SIFTS) (Q04673)
In PDB		Saccharomyces cerevisiae (baker's yeast)
201Tfb1polymer54358722.61Pfam (PF08567)
Pfam (PF03909)
UniProt (by SIFTS) (P32776)
In PDB		Saccharomyces cerevisiae (Baker's yeast)
217General transcription and DNA repair factor IIH helicase subunit XPBpolymer84395461.71UniProt (Q00578)
Pfam (PF13625)
Pfam (PF04851)
Pfam (PF16203)
In PDB		Saccharomyces cerevisiae (baker's yeast)TFIIH subunit XPB,DNA repair helicase RAD25,RNA polymerase II transcription factor B subunit SSL2,TFB subunit SSL2,Suppressor of stem-loop mutation 2
225General transcription and DNA repair factor IIH subunit TFB5polymer728243.51UniProt (Q3E7C1)
Pfam (PF06331)
In PDB		Saccharomyces cerevisiae (baker's yeast)TFIIH subunit TFB5,RNA polymerase II transcription factor B subunit 5
232RNA polymerase II transcription factor B subunit 2polymer51358602.31UniProt (A0A6A5Q2X3)
Pfam (PF03849)
Pfam (PF18307)
UniProt (by SIFTS) (Q02939)
In PDB		Saccharomyces cerevisiae (baker's yeast)
24XTranscription initiation factor IIE subunit betapolymer32837050.41UniProt (A0A6A5PS93)
Pfam (PF02186)
Pfam (PF18121)
Pfam (PF22254)
UniProt (by SIFTS) (P36145)
In PDB		Saccharomyces cerevisiae (baker's yeast)
25UTranscription initiation factor IIA large subunitpolymer28632230.81UniProt (A0A6A5Q2T8)
Pfam (PF03153)
UniProt (by SIFTS) (P32773)
In PDB		Saccharomyces cerevisiae (baker's yeast)Y55_G0039490.mRNA.1.CDS.1
26VTranscription initiation factor IIA subunit 2polymer12213473.11UniProt (A0A6A5PRZ0)
Pfam (PF02268)
Pfam (PF02751)
UniProt (by SIFTS) (P32774)
In PDB		Saccharomyces cerevisiae (baker's yeast)
27Nnon-template strand DNApolymer3811825.71Saccharomyces cerevisiae
28Ttemplate strand DNApolymer14834207.81Saccharomyces cerevisiae
29OTATA-box-binding proteinpolymer24027042.31UniProt (P13393)
Pfam (PF00352)
In PDB		Saccharomyces cerevisiae (baker's yeast)TATA sequence-binding protein,TBP,TATA-binding factor,TATA-box factor,Transcription factor D,Transcription initiation factor TFIID TBP subunit
30WTranscription initiation factor IIE subunit alphapolymer48254804.81UniProt (A0A6A5PTU5)
Pfam (PF02002)
UniProt (by SIFTS) (P36100)
In PDB		Saccharomyces cerevisiae (baker's yeast)
31PRNApolymer51649.11Saccharomyces cerevisiae
32M, A, B, C, I...ZINC IONnon-polymer65.415Chemie (ZN)
33AMAGNESIUM IONnon-polymer24.31Chemie (MG)
340IRON/SULFUR CLUSTERnon-polymer351.61Chemie (SF4)
Sequence modifications
4: 1 - 338 (UniProt: A0A7I9C5C2)
PDBExternal DatabaseDetails
Unk 113Asp 113conflict
Unk 114Met 114conflict
6: 1 - 461 (UniProt: A0A7I9FQL5)
PDBExternal DatabaseDetails
Unk 412Ile 412conflict
Unk 413Leu 413conflict
Unk 414Lys 414conflict
Unk 415Asn 415conflict
Unk 416His 416conflict
Unk 417Lys 417conflict
Unk 418Asn 418conflict
Unk 419Asp 419conflict
Unk 420Lys 420conflict
Unk 421Leu 421conflict
Unk 422Leu 422conflict
Unk 423Thr 423conflict
Unk 424Ser 424conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains31
Total formula weight1332105.0
Non-Polymers*Number of molecules17
Total formula weight1357.1
All*Total formula weight1333462.0
*Water molecules are not included.

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PDB entries from 2024-07-17

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