7MKX
Crystal Structure Analysis of human CDK2 and CCNA2 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Cyclin-dependent kinase 2 | polymer | 303 | 34467.9 | 2 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (Human) | Cell division protein kinase 2,p33 protein kinase |
2 | B, D | Cyclin-A2 | polymer | 268 | 30596.4 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) In PDB | Homo sapiens (Human) | Cyclin-A,Cyclin A |
3 | A, C | 2-[(5-bromo-2-{4-[(cyanomethyl)sulfamoyl]anilino}pyrimidin-4-yl)amino]-6-fluorobenzamide | non-polymer | 520.3 | 2 | Chemie (ZGY) |
Sequence modifications
A, C: 1 - 298 (UniProt: P24941)
B, D: 171 - 432 (UniProt: P20248)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Pro -3 | - | expression tag |
Leu -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 165 | - | expression tag |
Pro 166 | - | expression tag |
Leu 167 | - | expression tag |
Gly 168 | - | expression tag |
Ser 169 | - | expression tag |
Met 170 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 130128.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1040.7 | |
All* | Total formula weight | 131169.3 |